Paper Abstract and Keywords |
Presentation |
2007-10-19 13:25
Plasticity in cultured neuronal networks induced by electrical stimuli Yuzo Takayama, Hiroyuki Moriguchi, Yasuhiko Jimbo (Univ. Tokyo) NC2007-50 |
Abstract |
(in Japanese) |
(See Japanese page) |
(in English) |
It is widely recognized that activity-dependent synaptic plasticity plays a key role in learning and memory in biological information processing systems, however, little is known on the mechanisms for integrating such modifications on network-wide activity changes. In this paper, we studied effects of spation-temporally correlated electrical stimuli on the activity of neuronal network cultured on microelectrode arrays. We compared spatio-temporal patterns of the evoked responses between before and after repetitive application of correlated stimuli. After the correlated stimuli, the networks showed significantly different responses from those in the initial states. The modified activity reflected structures of the repeatedly applied correlated stimuli. The results suggested that spatio-temporally correlated inputs systematically induced modification of synaptic strengths in neuronal networks. |
Keyword |
(in Japanese) |
(See Japanese page) |
(in English) |
Plasticity / Electrical stimulation / Cultured neuronal networks / Microelectrode array / / / / |
Reference Info. |
IEICE Tech. Rep., vol. 107, no. 263, NC2007-50, pp. 93-97, Oct. 2007. |
Paper # |
NC2007-50 |
Date of Issue |
2007-10-11 (NC) |
ISSN |
Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
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NC2007-50 |
Conference Information |
Committee |
NC |
Conference Date |
2007-10-18 - 2007-10-19 |
Place (in Japanese) |
(See Japanese page) |
Place (in English) |
Tohoku University |
Topics (in Japanese) |
(See Japanese page) |
Topics (in English) |
Technology and Application of Brain Interface, General |
Paper Information |
Registration To |
NC |
Conference Code |
2007-10-NC |
Language |
Japanese |
Title (in Japanese) |
(See Japanese page) |
Sub Title (in Japanese) |
(See Japanese page) |
Title (in English) |
Plasticity in cultured neuronal networks induced by electrical stimuli |
Sub Title (in English) |
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Plasticity |
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Electrical stimulation |
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Cultured neuronal networks |
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Microelectrode array |
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1st Author's Name |
Yuzo Takayama |
1st Author's Affiliation |
University of Tokyo (Univ. Tokyo) |
2nd Author's Name |
Hiroyuki Moriguchi |
2nd Author's Affiliation |
University of Tokyo (Univ. Tokyo) |
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Yasuhiko Jimbo |
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University of Tokyo (Univ. Tokyo) |
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Speaker |
Author-1 |
Date Time |
2007-10-19 13:25:00 |
Presentation Time |
25 minutes |
Registration for |
NC |
Paper # |
NC2007-50 |
Volume (vol) |
vol.107 |
Number (no) |
no.263 |
Page |
pp.93-97 |
#Pages |
5 |
Date of Issue |
2007-10-11 (NC) |
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