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Paper Abstract and Keywords
Presentation 2007-10-19 13:25
Plasticity in cultured neuronal networks induced by electrical stimuli
Yuzo Takayama, Hiroyuki Moriguchi, Yasuhiko Jimbo (Univ. Tokyo) NC2007-50
Abstract (in Japanese) (See Japanese page) 
(in English) It is widely recognized that activity-dependent synaptic plasticity plays a key role in learning and memory in biological information processing systems, however, little is known on the mechanisms for integrating such modifications on network-wide activity changes. In this paper, we studied effects of spation-temporally correlated electrical stimuli on the activity of neuronal network cultured on microelectrode arrays. We compared spatio-temporal patterns of the evoked responses between before and after repetitive application of correlated stimuli. After the correlated stimuli, the networks showed significantly different responses from those in the initial states. The modified activity reflected structures of the repeatedly applied correlated stimuli. The results suggested that spatio-temporally correlated inputs systematically induced modification of synaptic strengths in neuronal networks.
Keyword (in Japanese) (See Japanese page) 
(in English) Plasticity / Electrical stimulation / Cultured neuronal networks / Microelectrode array / / / /  
Reference Info. IEICE Tech. Rep., vol. 107, no. 263, NC2007-50, pp. 93-97, Oct. 2007.
Paper # NC2007-50 
Date of Issue 2007-10-11 (NC) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
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reproduction
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee NC  
Conference Date 2007-10-18 - 2007-10-19 
Place (in Japanese) (See Japanese page) 
Place (in English) Tohoku University 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Technology and Application of Brain Interface, General 
Paper Information
Registration To NC 
Conference Code 2007-10-NC 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Plasticity in cultured neuronal networks induced by electrical stimuli 
Sub Title (in English)  
Keyword(1) Plasticity  
Keyword(2) Electrical stimulation  
Keyword(3) Cultured neuronal networks  
Keyword(4) Microelectrode array  
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1st Author's Name Yuzo Takayama  
1st Author's Affiliation University of Tokyo (Univ. Tokyo)
2nd Author's Name Hiroyuki Moriguchi  
2nd Author's Affiliation University of Tokyo (Univ. Tokyo)
3rd Author's Name Yasuhiko Jimbo  
3rd Author's Affiliation University of Tokyo (Univ. Tokyo)
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Speaker Author-1 
Date Time 2007-10-19 13:25:00 
Presentation Time 25 minutes 
Registration for NC 
Paper # NC2007-50 
Volume (vol) vol.107 
Number (no) no.263 
Page pp.93-97 
#Pages
Date of Issue 2007-10-11 (NC) 


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