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| Presentation | 2008-01-25 10:20 Simulation analyses on the neuronal responses to extracellular electrical stimulations -- Effects of stimulation pulse waveforms -- Katuki Tamanaha, Takao Kosai, Yuki Hayashida, Nobuki Murayama (Kumamoto Univ.)  MBE2007-80 |
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| Abstract | (in Japanese) | (See Japanese page) |
| (in English) | For neural diseases, clinical trials of the treatments/prostheses with the functional electric stimulation have been widely performed in recent years. In those cases, it is critical to use the minimum amounts of current/charge to stimulate the target neurons, in order to guarantee their safety. In this study, we made computer simulations using biophysics models of neurons, to analyze quantitatively how the threshold current/charge for eliciting neuronal excitation can be altered when different parameters of the pulse waveform were applied as the stimuli. As has been shown in our previous studies on retinal ganglion cells, the present simulations showed that the amounts of current/charge required for evoking spike firings of the model cells can be reduced by optimally adjusting the parameters of stimulation pulse waveforms. | |
| Keyword | (in Japanese) | (See Japanese page) |
| (in English) | neural prosthesis / electrical stimulation / neuron / biophysics model / computer simulation / / / | |
| Reference Info. | IEICE Tech. Rep., vol. 107, no. 460, MBE2007-80, pp. 5-8, Jan. 2008. | |
| Paper # | MBE2007-80 | |
| Date of Issue | 2008-01-18 (MBE) | |
| ISSN | Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 | |
| Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) | |
| Download PDF | MBE2007-80 |
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| Conference Information | |
| Committee | MBE |
| Conference Date | 2008-01-25 - 2008-01-25 |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Kyushu Univ. |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Paper Information | |
| Registration To | MBE |
| Conference Code | 2008-01-MBE |
| Language | Japanese |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Simulation analyses on the neuronal responses to extracellular electrical stimulations |
| Sub Title (in English) | Effects of stimulation pulse waveforms |
| Keyword(1) | neural prosthesis |
| Keyword(2) | electrical stimulation |
| Keyword(3) | neuron |
| Keyword(4) | biophysics model |
| Keyword(5) | computer simulation |
| Keyword(6) | |
| Keyword(7) | |
| Keyword(8) | |
| 1st Author's Name | Katuki Tamanaha |
| 1st Author's Affiliation | Kumamoto University (Kumamoto Univ.) |
| 2nd Author's Name | Takao Kosai |
| 2nd Author's Affiliation | Kumamoto University (Kumamoto Univ.) |
| 3rd Author's Name | Yuki Hayashida |
| 3rd Author's Affiliation | Kumamoto University (Kumamoto Univ.) |
| 4th Author's Name | Nobuki Murayama |
| 4th Author's Affiliation | Kumamoto University (Kumamoto Univ.) |
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| Speaker | Author-1 |
| Date Time | 2008-01-25 10:20:00 |
| Presentation Time | 20 minutes |
| Registration for | MBE |
| Paper # | MBE2007-80 |
| Volume (vol) | vol.107 |
| Number (no) | no.460 |
| Page | pp.5-8 |
| #Pages | 4 |
| Date of Issue | 2008-01-18 (MBE) |
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