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Paper Abstract and Keywords
Presentation 2010-11-05 15:30
[Poster Presentation] A Study on Multiple Multivariate Two-Sample Test for Gene Set Analysis using MST-based SVM Path-Following
Yuta Ishikawa, Kota Isobe, Masayuki Karasuyama, Taisuke Izumi, Ichiro Takeuchi (NIT) IBISML2010-88
Abstract (in Japanese) (See Japanese page) 
(in English) Microarray technology enables us to measure expression levels of thousands of genes simultaneously. We consider how to find differentially expressed gene sets between two samples. This task is called gene set analysis and it is formulated as multiple multivariate two-sample test. In this study, we introduce multiple multivariate two-sample test based on Support Vector Machine (SVM). In this approach, we have to train many label permuted SVMs in order to estimate the null distribution. To alleviate the computational difficulty, we propose an efficient algorithm for computing a set of label permuted SVMs using minimum spanning tree (MST) and path-following techniques.
Keyword (in Japanese) (See Japanese page) 
(in English) multivariate two-sample test / SVM / MST / path-following / gene set analysis / multiple testing / /  
Reference Info. IEICE Tech. Rep., vol. 110, no. 265, IBISML2010-88, pp. 211-220, Nov. 2010.
Paper # IBISML2010-88 
Date of Issue 2010-10-28 (IBISML) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee IBISML  
Conference Date 2010-11-04 - 2010-11-06 
Place (in Japanese) (See Japanese page) 
Place (in English) IIS, Univ. of Tokyo 
Topics (in Japanese) (See Japanese page) 
Topics (in English) IBIS 2010 (Workshop on Information-based Induction Sciences) 
Paper Information
Registration To IBISML 
Conference Code 2010-11-IBISML 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) A Study on Multiple Multivariate Two-Sample Test for Gene Set Analysis using MST-based SVM Path-Following 
Sub Title (in English)  
Keyword(1) multivariate two-sample test  
Keyword(2) SVM  
Keyword(3) MST  
Keyword(4) path-following  
Keyword(5) gene set analysis  
Keyword(6) multiple testing  
1st Author's Name Yuta Ishikawa  
1st Author's Affiliation Nagoya Institute of Technology (NIT)
2nd Author's Name Kota Isobe  
2nd Author's Affiliation Nagoya Institute of Technology (NIT)
3rd Author's Name Masayuki Karasuyama  
3rd Author's Affiliation Nagoya Institute of Technology (NIT)
4th Author's Name Taisuke Izumi  
4th Author's Affiliation Nagoya Institute of Technology (NIT)
5th Author's Name Ichiro Takeuchi  
5th Author's Affiliation Nagoya Institute of Technology (NIT)
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Speaker Author-1 
Date Time 2010-11-05 15:30:00 
Presentation Time 180 minutes 
Registration for IBISML 
Paper # IBISML2010-88 
Volume (vol) vol.110 
Number (no) no.265 
Page pp.211-220 
#Pages 10 
Date of Issue 2010-10-28 (IBISML) 

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