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| Presentation | 2011-01-20 10:15 Preliminary study of in-vivo liver measurement by optimized pulse sequence for MR elastography Ken Arai (Chiba Univ.), Mikio Suga (Chiba Univ./NIRS), Shinya Ozawa, Hajime Ikeda (Chiba Univ.), Masaya Hirano (GEHC-JP), Etsuko Kobayashi (Tokyo Univ.), Takayuki Obata (NIRS)  MI2010-89 |
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| Abstract | (in Japanese) | (See Japanese page) |
| (in English) | Magnetic resonance elastography (MRE) is a technique for quantitative and noninvasive assessment of tissue elasticity. MRE is often described as image-based palpation that can be used to characterize disease because the mechanical properties of tissues are often dramatically affected by the presence of disease processes. MRE pulse sequences obtain shear wave images by synchronizing motion sensitized gradients (MSG) with an external vibrator. A quantitative shear modulus map is calculated from the shear wave images. However, the magnitude property of the external vibrator and nonlinearity of the imaged object often induce unwanted higher harmonics that distort the shear wave images and impair the estimation of the elastic modulus. Additionally, bulk motion can induce signal loss, ghosting and unwanted phase accumulation. In this study, we apply the MSGs to gradient moment nulling (GMN) technique for reducing bulk motion effect and optimize them to minimize the contribution of higher harmonics to the shear wave images and therefore improve the accuracy of shear modulus estimation. Phantom and in-vivo study was performed to confirm the performance of the proposed MRE pulse sequence. The results show that the optimized MSG is able to acquire single frequency shear wave images even when large amplitude harmonic waves are present in the imaged object. Additionally, the proposed MRE pulse sequence reduced cardiac motion artifact. These results suggest that the proposed pulse sequence might be useful for in-vivo MRE studies. | |
| Keyword | (in Japanese) | (See Japanese page) |
| (in English) | MR elastography / pulse sequence / motion sensitizing gradients (MSG) / shear modulus measurement / MRI / / / | |
| Reference Info. | IEICE Tech. Rep., vol. 110, no. 364, MI2010-89, pp. 47-50, Jan. 2011. | |
| Paper # | MI2010-89 | |
| Date of Issue | 2011-01-12 (MI) | |
| ISSN | Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 | |
| Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) | |
| Download PDF | MI2010-89 |
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| Conference Information | |
| Committee | MI |
| Conference Date | 2011-01-19 - 2011-01-20 |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Naha-Bunka-Tembusu |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | General Medical Imaging |
| Paper Information | |
| Registration To | MI |
| Conference Code | 2011-01-MI |
| Language | Japanese |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Preliminary study of in-vivo liver measurement by optimized pulse sequence for MR elastography |
| Sub Title (in English) | |
| Keyword(1) | MR elastography |
| Keyword(2) | pulse sequence |
| Keyword(3) | motion sensitizing gradients (MSG) |
| Keyword(4) | shear modulus measurement |
| Keyword(5) | MRI |
| Keyword(6) | |
| Keyword(7) | |
| Keyword(8) | |
| 1st Author's Name | Ken Arai |
| 1st Author's Affiliation | Chiba University (Chiba Univ.) |
| 2nd Author's Name | Mikio Suga |
| 2nd Author's Affiliation | Chiba University/National Institute of Radiological Sciences (Chiba Univ./NIRS) |
| 3rd Author's Name | Shinya Ozawa |
| 3rd Author's Affiliation | Chiba University (Chiba Univ.) |
| 4th Author's Name | Hajime Ikeda |
| 4th Author's Affiliation | Chiba University (Chiba Univ.) |
| 5th Author's Name | Masaya Hirano |
| 5th Author's Affiliation | GE Healthcare Japan Corpolation (GEHC-JP) |
| 6th Author's Name | Etsuko Kobayashi |
| 6th Author's Affiliation | Tokyo University (Tokyo Univ.) |
| 7th Author's Name | Takayuki Obata |
| 7th Author's Affiliation | National Institute of Radiological Sciences (NIRS) |
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| Speaker | Author-1 |
| Date Time | 2011-01-20 10:15:00 |
| Presentation Time | 15 minutes |
| Registration for | MI |
| Paper # | MI2010-89 |
| Volume (vol) | vol.110 |
| Number (no) | no.364 |
| Page | pp.47-50 |
| #Pages | 4 |
| Date of Issue | 2011-01-12 (MI) |
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