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Paper Abstract and Keywords
Presentation 2011-06-23 15:15
Visualization of therapeutic ultrasound fields using image subtraction Schlieren technique -- Visualization of Fields in Small Chamber --
Hiroki Obara, Nobuki Kudo, Koichi Shimizu (Hokkaido Univ.) US2011-18
Abstract (in Japanese) (See Japanese page) 
(in English) Recently, there has been considerable interest in sonoporation, a technique to transduct drugs or genes into cells by ultrasound exposure. In typical studies of sonoporation using cultured cells, the cells and microbubbles are suspended in a culture dish with medium, and exposed to continuous ultrasound waves. In this situation, reflection of ultrasound at a medium-air interface and dish walls produces complex acoustic fields with various standing waves. In this study, the pressure fields of therapeutic ultrasound in a small chamber are visualized using a newly proposed technique called image-subtraction Schlieren. Observation results revealed that brightness of visualized fields is doubled in the presence of reflection and that brightness is decreased adjacent to the chamber wall. It was also confirmed that perturbation of water surface by acoustic streaming causes decrease in pressure amplitudes at antinodes. The linear relation found between brightness of the Schlieren images and acoustic pressure indicates the importance of the image-subtraction Schlieren technique for dosimetry of complex acoustic fields generated inside small chambers.
Keyword (in Japanese) (See Japanese page) 
(in English) ultrasound field / pressure distribution / visualization / Schlieren / image subtraction / / /  
Reference Info. IEICE Tech. Rep., vol. 111, no. 88, US2011-18, pp. 31-35, June 2011.
Paper # US2011-18 
Date of Issue 2011-06-16 (US) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
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reproduction
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee US  
Conference Date 2011-06-23 - 2011-06-23 
Place (in Japanese) (See Japanese page) 
Place (in English)  
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Paper Information
Registration To US 
Conference Code 2011-06-US 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Visualization of therapeutic ultrasound fields using image subtraction Schlieren technique 
Sub Title (in English) Visualization of Fields in Small Chamber 
Keyword(1) ultrasound field  
Keyword(2) pressure distribution  
Keyword(3) visualization  
Keyword(4) Schlieren  
Keyword(5) image subtraction  
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1st Author's Name Hiroki Obara  
1st Author's Affiliation Hokkaido University (Hokkaido Univ.)
2nd Author's Name Nobuki Kudo  
2nd Author's Affiliation Hokkaido University (Hokkaido Univ.)
3rd Author's Name Koichi Shimizu  
3rd Author's Affiliation Hokkaido University (Hokkaido Univ.)
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Speaker Author-1 
Date Time 2011-06-23 15:15:00 
Presentation Time 25 minutes 
Registration for US 
Paper # US2011-18 
Volume (vol) vol.111 
Number (no) no.88 
Page pp.31-35 
#Pages
Date of Issue 2011-06-16 (US) 


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