Paper Abstract and Keywords |
Presentation |
2012-03-16 16:00
Computational simulation with detailed model neurons of suppression in orbitofrontal cortex during deep brain stimulation of the nucleus accumbens Keigo Fukumoto, Yuta Kakimoto, Osamu Araki (TUS) MBE2011-146 |
Abstract |
(in Japanese) |
(See Japanese page) |
(in English) |
This study examined inhibitory activity in the orbitofrontal cortex in response to deep brain stimulation targeted on nucleus accumbens and the parameter values such as its magnitude and period. We modeled pyramidal neurons and inhibitory neuron with GABAergic receptors and connected them with a nucleus accumbens model neuron. As a result of numerical experiments,
larger magnitude and period, frequeny tends to induce higher activity of medium spiny neuron in nucleus accumbens. And We find out that the state of GABAergic receptor affect to inhibitory activity on orbitofrontal cortex. |
Keyword |
(in Japanese) |
(See Japanese page) |
(in English) |
Deep Brain Stimualtion / nucleus accumbens / orbitofrontal cortex / GABAergic receptor / model neurons / / / |
Reference Info. |
IEICE Tech. Rep., vol. 111, no. 482, MBE2011-146, pp. 201-206, March 2012. |
Paper # |
MBE2011-146 |
Date of Issue |
2012-03-07 (MBE) |
ISSN |
Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
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MBE2011-146 |
Conference Information |
Committee |
MBE NC |
Conference Date |
2012-03-14 - 2012-03-16 |
Place (in Japanese) |
(See Japanese page) |
Place (in English) |
Tamagawa University |
Topics (in Japanese) |
(See Japanese page) |
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Paper Information |
Registration To |
MBE |
Conference Code |
2012-03-MBE-NC |
Language |
Japanese |
Title (in Japanese) |
(See Japanese page) |
Sub Title (in Japanese) |
(See Japanese page) |
Title (in English) |
Computational simulation with detailed model neurons of suppression in orbitofrontal cortex during deep brain stimulation of the nucleus accumbens |
Sub Title (in English) |
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Deep Brain Stimualtion |
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nucleus accumbens |
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orbitofrontal cortex |
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GABAergic receptor |
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model neurons |
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1st Author's Name |
Keigo Fukumoto |
1st Author's Affiliation |
Tokyo University of Science (TUS) |
2nd Author's Name |
Yuta Kakimoto |
2nd Author's Affiliation |
Tokyo University of Science (TUS) |
3rd Author's Name |
Osamu Araki |
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Tokyo University of Science (TUS) |
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Speaker |
Author-1 |
Date Time |
2012-03-16 16:00:00 |
Presentation Time |
25 minutes |
Registration for |
MBE |
Paper # |
MBE2011-146 |
Volume (vol) |
vol.111 |
Number (no) |
no.482 |
Page |
pp.201-206 |
#Pages |
6 |
Date of Issue |
2012-03-07 (MBE) |