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| Presentation | 2013-01-26 11:45 Modulation of Neuronal Network Activity Using Magnetic Nanoparticle-Injected Astrocytes Yutaro Nakashima, Atsushi Saito, Kenta Shimba, Yuzo Takayama, Kiyoshi Kotani, Yasuhiko Jimbo (Univ. Tokyo)  MBE2012-87 |
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| Abstract | (in Japanese) | (See Japanese page) |
| (in English) | Recently, some previous studies reported that astrocytes, a type of glial cells, modulate the neuronal network functions such as synaptic transmission, density, and conduction of action potential. However, widespread modulations of network-wide activity of neuronal cells by astrocytes are unknown. In this study, we developed a 3-Dimensional co-culture system for the evaluation of neuronal-asrtocytic network interactions by using the magnetic nanoparticles injected astrocytes and the magnetic force. In the results, the astrocytic network integration elicited the unexpected inhibition of neuronal spontaneous activity. In addition, the selective activation of astrocytes evoked the modulation of neuronal network activity. | |
| Keyword | (in Japanese) | (See Japanese page) |
| (in English) | Neuronal Network / Astrocyte / Magnetic Nanoparticle / Microelectrode Array / Syncronized Burst / / / | |
| Reference Info. | IEICE Tech. Rep., vol. 112, no. 417, MBE2012-87, pp. 75-80, Jan. 2013. | |
| Paper # | MBE2012-87 | |
| Date of Issue | 2013-01-18 (MBE) | |
| ISSN | Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 | |
| Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) | |
| Download PDF | MBE2012-87 |
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| Conference Information | |
| Committee | MBE |
| Conference Date | 2013-01-25 - 2013-01-26 |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Kyushu Institute of Technologyy |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Paper Information | |
| Registration To | MBE |
| Conference Code | 2013-01-MBE |
| Language | Japanese |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Modulation of Neuronal Network Activity Using Magnetic Nanoparticle-Injected Astrocytes |
| Sub Title (in English) | |
| Keyword(1) | Neuronal Network |
| Keyword(2) | Astrocyte |
| Keyword(3) | Magnetic Nanoparticle |
| Keyword(4) | Microelectrode Array |
| Keyword(5) | Syncronized Burst |
| Keyword(6) | |
| Keyword(7) | |
| Keyword(8) | |
| 1st Author's Name | Yutaro Nakashima |
| 1st Author's Affiliation | University of Tokyo (Univ. Tokyo) |
| 2nd Author's Name | Atsushi Saito |
| 2nd Author's Affiliation | University of Tokyo (Univ. Tokyo) |
| 3rd Author's Name | Kenta Shimba |
| 3rd Author's Affiliation | University of Tokyo (Univ. Tokyo) |
| 4th Author's Name | Yuzo Takayama |
| 4th Author's Affiliation | University of Tokyo (Univ. Tokyo) |
| 5th Author's Name | Kiyoshi Kotani |
| 5th Author's Affiliation | University of Tokyo (Univ. Tokyo) |
| 6th Author's Name | Yasuhiko Jimbo |
| 6th Author's Affiliation | University of Tokyo (Univ. Tokyo) |
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| Speaker | Author-1 |
| Date Time | 2013-01-26 11:45:00 |
| Presentation Time | 25 minutes |
| Registration for | MBE |
| Paper # | MBE2012-87 |
| Volume (vol) | vol.112 |
| Number (no) | no.417 |
| Page | pp.75-80 |
| #Pages | 6 |
| Date of Issue | 2013-01-18 (MBE) |
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