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Paper Abstract and Keywords
Presentation 2013-11-22 15:25
[Invited Talk] Design and Construction of an Artificial Cell Model
Shin-ichiro M. Nomura (Tohoku Univ.) MBE2013-70 NC2013-51
Abstract (in Japanese) (See Japanese page) 
(in English) Producing an artificial models of cells by the use of materials that are compatible with living cells may be the most reasonable plan. In this contribution, here we present the results of some recent studies toward the construction of artificial cells, and explain methods for emulating several important specific functions of real cells in artificial liposomes. We discuss several aspects of the current experimental approaches, from the optimal construction of giant vesicles (GVs) to the realization of complex vesicle-based molecular system. The entrapment of bio molecules inside GVs are discussed, as well as the synthesis of water soluble proteins inside vesicles. We have also noted the “artificial” aspect of the cell models. It would be possible for the artificial structure in such models to perform a difficult task by designed artificial molecules by using DNA nanotechnology. Both approaches might contribute to produce basic component of a possible “biorobot", in a different way from genetically modified real-cells. We conclude with some general consideration about the future work on cell models using vesicles.
Keyword (in Japanese) (See Japanese page) 
(in English) Artificial cell / Giant liposome / Cell-free gene expression system / DNA nanotechnology / / / /  
Reference Info. IEICE Tech. Rep., vol. 113, no. 314, MBE2013-70, pp. 25-25, Nov. 2013.
Paper # MBE2013-70 
Date of Issue 2013-11-15 (MBE, NC) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
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reproduction
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee NC MBE  
Conference Date 2013-11-22 - 2013-11-23 
Place (in Japanese) (See Japanese page) 
Place (in English) Tohoku University 
Topics (in Japanese) (See Japanese page) 
Topics (in English) BCI/BMI, NC and MBE 
Paper Information
Registration To MBE 
Conference Code 2013-11-NC-MBE 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Design and Construction of an Artificial Cell Model 
Sub Title (in English)  
Keyword(1) Artificial cell  
Keyword(2) Giant liposome  
Keyword(3) Cell-free gene expression system  
Keyword(4) DNA nanotechnology  
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1st Author's Name Shin-ichiro M. Nomura  
1st Author's Affiliation Tohoku University (Tohoku Univ.)
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Speaker Author-1 
Date Time 2013-11-22 15:25:00 
Presentation Time 60 minutes 
Registration for MBE 
Paper # MBE2013-70, NC2013-51 
Volume (vol) vol.113 
Number (no) no.314(MBE), no.315(NC) 
Page p.25(MBE), p.29(NC) 
#Pages
Date of Issue 2013-11-15 (MBE, NC) 


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