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Paper Abstract and Keywords
Presentation 2019-01-23 09:50
Analysis of a Hodgkin-Huxley-type model of human atrial myocytes -- Focusing on the treatment of ionic concentration variables --
Rikutaro Inoshi, Shinji Doi (Kyoto Univ.) NLP2018-97
Abstract (in Japanese) (See Japanese page) 
(in English) The electrical signal (action potential) from the sinoatrial node is transmitted to cardiomyocytes in the atrium and ventricle, creating a heartbeat.
The action potential is crucial to maintain our life activity.
Because it is difficult to investigate the generation mechanism of the action potential using only a physiological experiment, we use the Hodgkin--Huxley-type mathematical model~¥cite{HH} to describe the action potential of cardiomyocytes.
Recently, physiological experiments have been developed and many models including ion concentrations as variables have been proposed, however, some problems of such models are reported¥cite{varghese,thomas}.
The purpose of this study is to study on the treatment of concentration variables using a human atrial cell model.
In this paper, fixing the concentration variables as constants and treating them as bifurcation parameters, we perform bifurcation analysis.
Thus, we analyze the effects of the concentration variables on the action potential.
Keyword (in Japanese) (See Japanese page) 
(in English) Hodgkin--Huxley-type model / Human atrial cell / Ionic concentration variable / Bifurcation analysis / / / /  
Reference Info. IEICE Tech. Rep., vol. 118, no. 413, NLP2018-97, pp. 5-10, Jan. 2019.
Paper # NLP2018-97 
Date of Issue 2019-01-16 (NLP) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
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All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee NLP NC  
Conference Date 2019-01-23 - 2019-01-24 
Place (in Japanese) (See Japanese page) 
Place (in English) The Centennial Hall, Hokkaido Univ. 
Topics (in Japanese) (See Japanese page) 
Topics (in English) General Implementation of Neuro Computing, Analysis and Modeling of Human Science, etc. 
Paper Information
Registration To NLP 
Conference Code 2019-01-NLP-NC 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Analysis of a Hodgkin-Huxley-type model of human atrial myocytes 
Sub Title (in English) Focusing on the treatment of ionic concentration variables 
Keyword(1) Hodgkin--Huxley-type model  
Keyword(2) Human atrial cell  
Keyword(3) Ionic concentration variable  
Keyword(4) Bifurcation analysis  
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1st Author's Name Rikutaro Inoshi  
1st Author's Affiliation Kyoto University (Kyoto Univ.)
2nd Author's Name Shinji Doi  
2nd Author's Affiliation Kyoto University (Kyoto Univ.)
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Speaker Author-1 
Date Time 2019-01-23 09:50:00 
Presentation Time 20 minutes 
Registration for NLP 
Paper # NLP2018-97 
Volume (vol) vol.118 
Number (no) no.413 
Page pp.5-10 
#Pages
Date of Issue 2019-01-16 (NLP) 


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