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Paper Abstract and Keywords
Presentation 2019-02-08 10:45
Development of Phenotyping algorithm from Medical Text-based Data using Machine Learning Methods
Takanori Yamashita, Rieko Izukura, Sachio Hirokawa, Naoki Nakashima (Kyushu Univ.) NLC2018-45
Abstract (in Japanese) (See Japanese page) 
(in English) Electronic medical records (EMRs) accumulated in the Hospital Information System (HIS) are called Real World Data (RWD). Utilization of RWD can help advance promising treatments, detect side effects detection, and improve the efficiency of previously-unknown medical treatment which were unknown in previous clinical research and intervention studies. We must develop some phenotyping algorithms to ensure high performance from RWD. Although drugs, laboratory tests, diagnoses and surgeries can be expressed as structured data, patient symptoms, the rationales for various medical treatments and the patient outcomes are often described in free-text format. In this research, we aimed to develop true Interstitial Pneumonia case extraction an algorithm from unstructured text-based data. 48 cases were diagnosed Interstitial pneumonia by chest physician from CT reports of sampling 100 cases. Three machine learning methods (Support Vector Machine, Feature Selection and Gradient Boosting Decision Tree) were combined for development of text corresponding phenotyping. We extracted 6 keywords as feature word from its score using machine learning methods, and PPV is 0.483 and sensitivity is 0.875 when one of them is included.
Keyword (in Japanese) (See Japanese page) 
(in English) Interstitial pneumonia / SVM / GBDT / Phenotyping / / / /  
Reference Info. IEICE Tech. Rep., vol. 118, no. 439, NLC2018-45, pp. 53-57, Feb. 2019.
Paper # NLC2018-45 
Date of Issue 2019-01-31 (NLC) 
ISSN Online edition: ISSN 2432-6380
Copyright
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All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee NLC IPSJ-IFAT  
Conference Date 2019-02-07 - 2019-02-08 
Place (in Japanese) (See Japanese page) 
Place (in English) Ryukoku University Omiya Campus 
Topics (in Japanese) (See Japanese page) 
Topics (in English) The 14th Text Analytics Symposium 
Paper Information
Registration To NLC 
Conference Code 2019-02-NLC-IFAT 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Development of Phenotyping algorithm from Medical Text-based Data using Machine Learning Methods 
Sub Title (in English)  
Keyword(1) Interstitial pneumonia  
Keyword(2) SVM  
Keyword(3) GBDT  
Keyword(4) Phenotyping  
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1st Author's Name Takanori Yamashita  
1st Author's Affiliation Kyushu University (Kyushu Univ.)
2nd Author's Name Rieko Izukura  
2nd Author's Affiliation Kyushu University (Kyushu Univ.)
3rd Author's Name Sachio Hirokawa  
3rd Author's Affiliation Kyushu University (Kyushu Univ.)
4th Author's Name Naoki Nakashima  
4th Author's Affiliation Kyushu University (Kyushu Univ.)
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Speaker Author-1 
Date Time 2019-02-08 10:45:00 
Presentation Time 25 minutes 
Registration for NLC 
Paper # NLC2018-45 
Volume (vol) vol.118 
Number (no) no.439 
Page pp.53-57 
#Pages
Date of Issue 2019-01-31 (NLC) 


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