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Paper Abstract and Keywords
Presentation 2021-02-19 16:25
Development and application of a highly sensitive color vision system
Masatoshi Kitaguchi, Sayumi Tsuyuguchi, Miwa Hashizume, Ayuka Kato, Tomoyuki Naito, Hiromichi Sato (Osaka Univ.) HIP2020-91
Abstract (in Japanese) (See Japanese page) 
(in English) Dystrophinopathy is a progressive intractable disease that is caused by an abnormality in the gene for the causative protein dystrophin, leads to degeneration and necrosis of skeletal muscle, and is known to also occur in the retina and brain. However, no systematic method has been established to examine the progress and extent of the disease over time. Painful and invasive methods, such as skeletal muscle biopsy, are used to examine the status of the disease in individual cases and are particularly distressing for patients who develop the disease at an early age, such as 2 or 3 years old. In this study, we focused on the abnormalities of red–green color vision based on patients’ paintings in previous studies and developed a simple color vision test system that can be used in the supine and prone positions on a bed. The results showed an association between the dystrophin gene isoform mutations that trigger the disease and a decrease in sensitivity to both red and green based on a tendency toward visual sensitivity to both luminance and hue. This suggests the possibility of monitoring the progress of the disease using a simple, non-invasive color vision test.
Keyword (in Japanese) (See Japanese page) 
(in English) color blindness test / dystrophinopathy / retina / cone / luminance / isofome / gene /  
Reference Info. IEICE Tech. Rep., vol. 120, no. 375, HIP2020-91, pp. 78-83, Feb. 2021.
Paper # HIP2020-91 
Date of Issue 2021-02-11 (HIP) 
ISSN Online edition: ISSN 2432-6380
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All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee HIP VRSJ  
Conference Date 2021-02-18 - 2021-02-19 
Place (in Japanese) (See Japanese page) 
Place (in English) Online 
Topics (in Japanese) (See Japanese page) 
Topics (in English)  
Paper Information
Registration To HIP 
Conference Code 2021-02-HIP 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Development and application of a highly sensitive color vision system 
Sub Title (in English)  
Keyword(1) color blindness test  
Keyword(2) dystrophinopathy  
Keyword(3) retina  
Keyword(4) cone  
Keyword(5) luminance  
Keyword(6) isofome  
Keyword(7) gene  
Keyword(8)  
1st Author's Name Masatoshi Kitaguchi  
1st Author's Affiliation Osaka University (Osaka Univ.)
2nd Author's Name Sayumi Tsuyuguchi  
2nd Author's Affiliation Osaka University (Osaka Univ.)
3rd Author's Name Miwa Hashizume  
3rd Author's Affiliation Osaka University (Osaka Univ.)
4th Author's Name Ayuka Kato  
4th Author's Affiliation Osaka University (Osaka Univ.)
5th Author's Name Tomoyuki Naito  
5th Author's Affiliation Osaka University (Osaka Univ.)
6th Author's Name Hiromichi Sato  
6th Author's Affiliation Osaka University (Osaka Univ.)
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Speaker Author-1 
Date Time 2021-02-19 16:25:00 
Presentation Time 25 minutes 
Registration for HIP 
Paper # HIP2020-91 
Volume (vol) vol.120 
Number (no) no.375 
Page pp.78-83 
#Pages
Date of Issue 2021-02-11 (HIP) 


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