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| Presentation | 2007-07-21 16:40 Evaluation of dynamic changes of nitric oxide and its related factors in dialysate of peritoneal dialysis Aya Takayama (Kawasaki Univ. / Okayama Univ.), Seiichi Mochizuki, Mayumi Ono (Kawasaki Medical Sch. / Kawasaki Univ.), Toyotaka Yada, Yasuo Ogasawara (Kawasaki Medical Sch.), Tamaki Sasaki (Kawasaki Medical Sch. / Kawasaki Univ.), Tomoki Kitawaki, Hisao Oka (Okayama Univ.)  MBE2007-42 |
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| Abstract | (in Japanese) | (See Japanese page) |
| (in English) | It has been speculated that dysfunction of the peritoneal membrane including loss of ultrafiltration capacity is related with abnormal production and/or metabolism of endogenous nitric oxide (NO). Tetrahydrobiopterin (BH4) is a key cofactor of nitric oxide synthase (NOS) to maintain the NOS activity. The aim of this study was thus to measure concentrations of NO and its related factors in peritoneal dialysis solutions in CAPD patients to study the possible involvement of NO in the peritoneal dysfunction. NO and BH4 concentrations were significantly higher in the dialysate after 5-6 hr CAPD than in the dialysate immediately after an exchange of CAPD solution. Both NO and BH4 tended to increase in the time course, and thus it was suggested that NO be produced from the peritoneal and surrounding tissues and that BH4 be involved in the changes in NO production. Direct measurement of NO concentration will thus contribute to investigation of possible involvement of NO in the changes in peritoneal membrane functions in CAPD. | |
| Keyword | (in Japanese) | (See Japanese page) |
| (in English) | continuous ambulatory peritoneal dialysis (CAPD) / nitric oxide (NO) / nitric oxide synthase (NOS) / tetrahydrobiopterin (BH4) / NO sensor / dialysate / / | |
| Reference Info. | IEICE Tech. Rep., vol. 107, no. 154, MBE2007-42, pp. 87-90, July 2007. | |
| Paper # | MBE2007-42 | |
| Date of Issue | 2007-07-13 (MBE) | |
| ISSN | Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 | |
| Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) | |
| Download PDF | MBE2007-42 |
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| Conference Information | |
| Committee | MBE |
| Conference Date | 2007-07-20 - 2007-07-21 |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Paper Information | |
| Registration To | MBE |
| Conference Code | 2007-07-MBE |
| Language | Japanese |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Evaluation of dynamic changes of nitric oxide and its related factors in dialysate of peritoneal dialysis |
| Sub Title (in English) | |
| Keyword(1) | continuous ambulatory peritoneal dialysis (CAPD) |
| Keyword(2) | nitric oxide (NO) |
| Keyword(3) | nitric oxide synthase (NOS) |
| Keyword(4) | tetrahydrobiopterin (BH4) |
| Keyword(5) | NO sensor |
| Keyword(6) | dialysate |
| Keyword(7) | |
| Keyword(8) | |
| 1st Author's Name | Aya Takayama |
| 1st Author's Affiliation | Kawasaki Univercity of Medical Welfare / Okayama University (Kawasaki Univ. / Okayama Univ.) |
| 2nd Author's Name | Seiichi Mochizuki |
| 2nd Author's Affiliation | Kawasaki Medical School / Kawasaki Univercity of Medical Welfare (Kawasaki Medical Sch. / Kawasaki Univ.) |
| 3rd Author's Name | Mayumi Ono |
| 3rd Author's Affiliation | Kawasaki Medical School / Kawasaki Univercity of Medical Welfare (Kawasaki Medical Sch. / Kawasaki Univ.) |
| 4th Author's Name | Toyotaka Yada |
| 4th Author's Affiliation | Kawasaki Medical School (Kawasaki Medical Sch.) |
| 5th Author's Name | Yasuo Ogasawara |
| 5th Author's Affiliation | Kawasaki Medical School (Kawasaki Medical Sch.) |
| 6th Author's Name | Tamaki Sasaki |
| 6th Author's Affiliation | Kawasaki Medical School / Kawasaki Univercity of Medical Welfare (Kawasaki Medical Sch. / Kawasaki Univ.) |
| 7th Author's Name | Tomoki Kitawaki |
| 7th Author's Affiliation | Okayama University (Okayama Univ.) |
| 8th Author's Name | Hisao Oka |
| 8th Author's Affiliation | Okayama University (Okayama Univ.) |
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| Speaker | Author-1 |
| Date Time | 2007-07-21 16:40:00 |
| Presentation Time | 25 minutes |
| Registration for | MBE |
| Paper # | MBE2007-42 |
| Volume (vol) | vol.107 |
| Number (no) | no.154 |
| Page | pp.87-90 |
| #Pages | 4 |
| Date of Issue | 2007-07-13 (MBE) |
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