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Paper Abstract and Keywords
Presentation 2007-08-10 11:30
Protective mechanism of the inner ear from traumatic noise exposure actuated by heat stress
Michio Murakoshi, Naohiro Yoshida, Yoko Kitsunai, Koji Iida, Shun Kumano, Takashi Suzuki, Toshimitsu Kobayashi, Hiroshi Wada (Tohoku Univ.) EA2007-49
Abstract (in Japanese) (See Japanese page) 
(in English) Noise-induced hearing loss was reported to be decreased by raising the body temperature before traumatic noise exposure, i.e., heat stress. However, the protective mechanism of the inner ear against such traumatic exposure remains unknown. In the present study, the mechanical properties and the amount of filamentous actin of outer hair cells (OHCs) in mice with or without heat stress were measured by atomic force microscopy and confocal laser scanning microscopy, respectively. The conditioning by heat stress caused an increase in F-actin of the OHCs, leading to an increase in their Young’s modulus. These results suggest that OHCs exposed to prior heat stress possibly experience less strain when they are exposed to loud noise, resulting in protection from traumatic noise exposure.
Keyword (in Japanese) (See Japanese page) 
(in English) Heat Stress / Outer Hair Cell / Young's Modulus / Filamentous Actin / Prestin / Heat Shock Protein / Distortion Product Otoacoustic Emission / Atomic Force Microscopy  
Reference Info. IEICE Tech. Rep., vol. 107, no. 187, EA2007-49, pp. 19-24, Aug. 2007.
Paper # EA2007-49 
Date of Issue 2007-08-03 (EA) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
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reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee EA  
Conference Date 2007-08-09 - 2007-08-10 
Place (in Japanese) (See Japanese page) 
Place (in English) School of Engineering, Tohoku University 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Hearing, Audio Signal Processing, etc. 
Paper Information
Registration To EA 
Conference Code 2007-08-EA 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Protective mechanism of the inner ear from traumatic noise exposure actuated by heat stress 
Sub Title (in English)  
Keyword(1) Heat Stress  
Keyword(2) Outer Hair Cell  
Keyword(3) Young's Modulus  
Keyword(4) Filamentous Actin  
Keyword(5) Prestin  
Keyword(6) Heat Shock Protein  
Keyword(7) Distortion Product Otoacoustic Emission  
Keyword(8) Atomic Force Microscopy  
1st Author's Name Michio Murakoshi  
1st Author's Affiliation Tohoku University (Tohoku Univ.)
2nd Author's Name Naohiro Yoshida  
2nd Author's Affiliation Tohoku University (Tohoku Univ.)
3rd Author's Name Yoko Kitsunai  
3rd Author's Affiliation Tohoku University (Tohoku Univ.)
4th Author's Name Koji Iida  
4th Author's Affiliation Tohoku University (Tohoku Univ.)
5th Author's Name Shun Kumano  
5th Author's Affiliation Tohoku University (Tohoku Univ.)
6th Author's Name Takashi Suzuki  
6th Author's Affiliation Tohoku University (Tohoku Univ.)
7th Author's Name Toshimitsu Kobayashi  
7th Author's Affiliation Tohoku University (Tohoku Univ.)
8th Author's Name Hiroshi Wada  
8th Author's Affiliation Tohoku University (Tohoku Univ.)
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Speaker Author-1 
Date Time 2007-08-10 11:30:00 
Presentation Time 30 minutes 
Registration for EA 
Paper # EA2007-49 
Volume (vol) vol.107 
Number (no) no.187 
Page pp.19-24 
#Pages 6 
Date of Issue 2007-08-03 (EA) 

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