| Paper Abstract and Keywords |
| Presentation |
2007-12-22 13:55
A mathematical model of a retinal rod photoreceptor network Yusuke Miyamoto, Yoshimi Kamiyama (Aichi Prefectural Univ) NC2007-80 |
| Abstract |
(in Japanese) |
(See Japanese page) |
| (in English) |
In this study, to analyze the underlying mechanism of rod photoresponses, we developed a mathematical model of the rod network based on anatomical and neurophysiological findings. We modeled single rod photoreceptor with five ionic currents ($I_{Ca}, I_{Kv}, I_{Cl(Ca)}, I_{K(Ca)}, I_{l}$), intracellular calcium system and phototransduction mechanism. Each rod compartment was connected by gap conductance according to the finding on rod electrical coupling (Zhang and Wu, 2004). In simulation, the responses of the model produced by small and large spots were in good agreement with the experimental results. The time course of the photoresponse produced in the rod model depended upon the area of illumination. Our results suggest that the ionic mechanisms of single rod itself can account for these photoresponses. |
| Keyword |
(in Japanese) |
(See Japanese page) |
| (in English) |
mathematical model / rod network / photoreceptor / retina / / / / |
| Reference Info. |
IEICE Tech. Rep., vol. 107, no. 410, NC2007-80, pp. 53-58, Dec. 2007. |
| Paper # |
NC2007-80 |
| Date of Issue |
2007-12-15 (NC) |
| ISSN |
Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
| Download PDF |
NC2007-80 |
| Conference Information |
| Committee |
MBE NC |
| Conference Date |
2007-12-22 - 2007-12-22 |
| Place (in Japanese) |
(See Japanese page) |
| Place (in English) |
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| Topics (in Japanese) |
(See Japanese page) |
| Topics (in English) |
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| Paper Information |
| Registration To |
NC |
| Conference Code |
2007-12-MBE-NC |
| Language |
Japanese |
| Title (in Japanese) |
(See Japanese page) |
| Sub Title (in Japanese) |
(See Japanese page) |
| Title (in English) |
A mathematical model of a retinal rod photoreceptor network |
| Sub Title (in English) |
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| Keyword(1) |
mathematical model |
| Keyword(2) |
rod network |
| Keyword(3) |
photoreceptor |
| Keyword(4) |
retina |
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| 1st Author's Name |
Yusuke Miyamoto |
| 1st Author's Affiliation |
Aichi Prefectural University (Aichi Prefectural Univ) |
| 2nd Author's Name |
Yoshimi Kamiyama |
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Aichi Prefectural University (Aichi Prefectural Univ) |
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| Speaker |
Author-1 |
| Date Time |
2007-12-22 13:55:00 |
| Presentation Time |
25 minutes |
| Registration for |
NC |
| Paper # |
NC2007-80 |
| Volume (vol) |
vol.107 |
| Number (no) |
no.410 |
| Page |
pp.53-58 |
| #Pages |
6 |
| Date of Issue |
2007-12-15 (NC) |