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Paper Abstract and Keywords
Presentation 2009-10-01 13:30
Development of a multifunctional CMOS image sensor for in vivo sensing of neural activities in a mouse deep brain
Ayato Tagawa, Hiroki Mitani, Masahiro Mitani (NAIST), Toshihiko Noda, Kiyotaka Sasagawa, Takashi Tokuda, Jun Ohta (NAIST/JST) ICD2009-41
Abstract (in Japanese) (See Japanese page) 
(in English) We developed a multimodal CMOS image sensor includes an pixel array, electrodes, and LED. The electrodes were placed on the pixel array. Windows were opened in the electrode over the photodiodes to enable the fluorescence to be imaged using the pixels under the electrodes. An LED was mounted on the chip for miniaturization and the sensor chip was shaped like a shank to facilitate smooth insertion into the brain tissue. In a brain phantom, the change in the electrical potential was successfully sensed by the electrode, and green fluorescent beads were simultaneously imaged using the pixels under the electrode. We also demonstrated that the device could successfully operate in deep brain of an anesthetized mouse.
Keyword (in Japanese) (See Japanese page) 
(in English) image sensor / electrode / brain functional imaging / in vivo / fluorescent imaging / bioimaging / /  
Reference Info. IEICE Tech. Rep., vol. 109, pp. 39-43, Oct. 2009.
Paper #  
Date of Issue 2009-09-24 (ICD) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
and
reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF ICD2009-41

Conference Information
Committee ICD ITE-IST  
Conference Date 2009-10-01 - 2009-10-02 
Place (in Japanese) (See Japanese page) 
Place (in English) CIC Tokyo (Tamachi) 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Analog, Mixed analog and digital, RF, and sensor interface circuitry 
Paper Information
Registration To ITE-IST 
Conference Code 2009-10-ICD-IST 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Development of a multifunctional CMOS image sensor for in vivo sensing of neural activities in a mouse deep brain 
Sub Title (in English)  
Keyword(1) image sensor  
Keyword(2) electrode  
Keyword(3) brain functional imaging  
Keyword(4) in vivo  
Keyword(5) fluorescent imaging  
Keyword(6) bioimaging  
Keyword(7)  
Keyword(8)  
1st Author's Name Ayato Tagawa  
1st Author's Affiliation Nara Institute Science and Technology (NAIST)
2nd Author's Name Hiroki Mitani  
2nd Author's Affiliation Nara Institute Science and Technology (NAIST)
3rd Author's Name Masahiro Mitani  
3rd Author's Affiliation Nara Institute Science and Technology (NAIST)
4th Author's Name Toshihiko Noda  
4th Author's Affiliation Nara Institute Science and Technology/JST-CREST (NAIST/JST)
5th Author's Name Kiyotaka Sasagawa  
5th Author's Affiliation Nara Institute Science and Technology/JST-CREST (NAIST/JST)
6th Author's Name Takashi Tokuda  
6th Author's Affiliation Nara Institute Science and Technology/JST-CREST (NAIST/JST)
7th Author's Name Jun Ohta  
7th Author's Affiliation Nara Institute Science and Technology/JST-CREST (NAIST/JST)
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Speaker Author-1 
Date Time 2009-10-01 13:30:00 
Presentation Time 25 minutes 
Registration for ITE-IST 
Paper # ICD2009-41 
Volume (vol) vol.109 
Number (no) no.214 
Page pp.39-43 
#Pages 5 
Date of Issue 2009-09-24 (ICD) 

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