Paper Abstract and Keywords |
Presentation |
2010-01-26 13:25
Study on exclusive monitoring of blood coagulation in dialysis circuit Toshio Sato, Yosuke Mizushima, Kanako Niizuma, Ayako Murakami, Yuka Motohashi, Norimichi Kawashima (Toin Univ. of Yokohama.), Tetsuzo Agishi (Fureai Machida Hospital) US2009-106 |
Abstract |
(in Japanese) |
(See Japanese page) |
(in English) |
For preventing coagulation in the dialysis circuit during hemodialysis, an anticoagulant is injected continuously at a constant rate. At many institutions, activated clotting coagulation time (ACT) is measured for adjusting this rate. However, ACT is not sufficient for determining the injection volume of anticoagulants. This is because ACT is not a reliable parameter for hemorrhagic patients. Dialysis circuit failure due to coagulation is highly detrimental to patients. We have investigated a non-contact method to monitor blood coagulation in dialysis circuit. Since the amplitude spectrum of the ultrasonic wave propagating through an intravenous drip chamber of the dialysis circuit should change when coagulation in the dialysis circuit occurs, we decided to employ ultrasonic for monitoring. A clip type ultrasonic probe was installed to the two positions of the drip chamber. A dialysis circuit was filled up with cow blood. The drip chamber was irradiated with ultrasonic waves of 3MHz, 5MHz and 7MHz operating frequency. The changes of the amplitude spectrum of ultrasonic wave in progressing coagulation after adding calcium chloride were measured. The amplitude spectrum increased with simultaneously increasing of the pressure in the dialysis circuit. We also confirmed that the amplitude spectrum only responded the incidence of coagulation in the dialysis circuit. |
Keyword |
(in Japanese) |
(See Japanese page) |
(in English) |
Hemodialysis / Blood coagulation in dialysis circuit / Ultrasonic probe / Amplitude spectrum / / / / |
Reference Info. |
IEICE Tech. Rep., vol. 109, no. 388, US2009-106, pp. 105-110, Jan. 2010. |
Paper # |
US2009-106 |
Date of Issue |
2010-01-18 (US) |
ISSN |
Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 |
Copyright and reproduction |
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US2009-106 |
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