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Presentation 2010-01-26 13:25
Study on exclusive monitoring of blood coagulation in dialysis circuit
Toshio Sato, Yosuke Mizushima, Kanako Niizuma, Ayako Murakami, Yuka Motohashi, Norimichi Kawashima (Toin Univ. of Yokohama.), Tetsuzo Agishi (Fureai Machida Hospital) US2009-106
Abstract (in Japanese) (See Japanese page) 
(in English) For preventing coagulation in the dialysis circuit during hemodialysis, an anticoagulant is injected continuously at a constant rate. At many institutions, activated clotting coagulation time (ACT) is measured for adjusting this rate. However, ACT is not sufficient for determining the injection volume of anticoagulants. This is because ACT is not a reliable parameter for hemorrhagic patients. Dialysis circuit failure due to coagulation is highly detrimental to patients. We have investigated a non-contact method to monitor blood coagulation in dialysis circuit. Since the amplitude spectrum of the ultrasonic wave propagating through an intravenous drip chamber of the dialysis circuit should change when coagulation in the dialysis circuit occurs, we decided to employ ultrasonic for monitoring. A clip type ultrasonic probe was installed to the two positions of the drip chamber. A dialysis circuit was filled up with cow blood. The drip chamber was irradiated with ultrasonic waves of 3MHz, 5MHz and 7MHz operating frequency. The changes of the amplitude spectrum of ultrasonic wave in progressing coagulation after adding calcium chloride were measured. The amplitude spectrum increased with simultaneously increasing of the pressure in the dialysis circuit. We also confirmed that the amplitude spectrum only responded the incidence of coagulation in the dialysis circuit.
Keyword (in Japanese) (See Japanese page) 
(in English) Hemodialysis / Blood coagulation in dialysis circuit / Ultrasonic probe / Amplitude spectrum / / / /  
Reference Info. IEICE Tech. Rep., vol. 109, no. 388, US2009-106, pp. 105-110, Jan. 2010.
Paper # US2009-106 
Date of Issue 2010-01-18 (US) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
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All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee EA US  
Conference Date 2010-01-25 - 2010-01-26 
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Paper Information
Registration To US 
Conference Code 2010-01-EA-US 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Study on exclusive monitoring of blood coagulation in dialysis circuit 
Sub Title (in English)  
Keyword(1) Hemodialysis  
Keyword(2) Blood coagulation in dialysis circuit  
Keyword(3) Ultrasonic probe  
Keyword(4) Amplitude spectrum  
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1st Author's Name Toshio Sato  
1st Author's Affiliation Toin University of Yokohama (Toin Univ. of Yokohama.)
2nd Author's Name Yosuke Mizushima  
2nd Author's Affiliation Toin University of Yokohama (Toin Univ. of Yokohama.)
3rd Author's Name Kanako Niizuma  
3rd Author's Affiliation Toin University of Yokohama (Toin Univ. of Yokohama.)
4th Author's Name Ayako Murakami  
4th Author's Affiliation Toin University of Yokohama (Toin Univ. of Yokohama.)
5th Author's Name Yuka Motohashi  
5th Author's Affiliation Toin University of Yokohama (Toin Univ. of Yokohama.)
6th Author's Name Norimichi Kawashima  
6th Author's Affiliation Toin University of Yokohama (Toin Univ. of Yokohama.)
7th Author's Name Tetsuzo Agishi  
7th Author's Affiliation Fureai Machida Hospital (Fureai Machida Hospital)
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Speaker Author-1 
Date Time 2010-01-26 13:25:00 
Presentation Time 25 minutes 
Registration for US 
Paper # US2009-106 
Volume (vol) vol.109 
Number (no) no.388 
Page pp.105-110 
#Pages
Date of Issue 2010-01-18 (US) 


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