Paper Abstract and Keywords |
Presentation |
2010-01-28 11:40
Computer-aided Classification of Patients with Dementia of Alzheimer's Type Based on Cerebral Blood Flow Map Determined by Arterial Spin Labeling Yasuo Yamashita, Hidetaka Arimura, Takashi Yoshiura, Taiki Magome, Koji Kobayashi, Akira Monji, Fukai Toyofuku, Masafumi Ohki, Yasuhiko Nakamura, Hiroshi Honda (Kyushu Univ.) MI2009-95 |
Abstract |
(in Japanese) |
(See Japanese page) |
(in English) |
Arterial spin labeling (ASL) is one of MR imaging techniques for measurement of cerebral blood flow (CBF) without using the contrast medium. The CBF map image measured by the ASL imaging can be used to help discriminate individuals with Alzheimer’s disease (AD) from normal subjects. We have developed a computerized classification method for patients with AD based on CBF map obtained by the ASL technique. The average CBFs in cortical regions of cerebral lobes were determined by using a free-form deformation between ALS image and the Talairach brain atlas. Finally, an artificial neural network, which was trained by the average CBFs in cortical regions, was employed for distinguishing patients with AD from control subjects. We applied the proposed method to 10 patients with AD and 10 control subjects. As a result, all cases could be classified correctly in the evaluation of resubstitution test. |
Keyword |
(in Japanese) |
(See Japanese page) |
(in English) |
Alzheimer’s disease (AD) / arterial spin labeling (ASL) / computer-aided diagnosis / / / / / |
Reference Info. |
IEICE Tech. Rep., vol. 109, no. 407, MI2009-95, pp. 107-109, Jan. 2010. |
Paper # |
MI2009-95 |
Date of Issue |
2010-01-21 (MI) |
ISSN |
Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
Download PDF |
MI2009-95 |
|