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Paper Abstract and Keywords
Presentation 2011-02-21 10:10
Accuracy analysis of echo amplitude distribution model for fibrotic liver
Yu Igarashi (Tokyo Inst. of Tech.), Tadashi Yamaguchi (Chiba Univ.), Hiroyuki Hachiya (Tokyo Inst. of Tech.) US2010-113
Abstract (in Japanese) (See Japanese page) 
(in English) We have presented a new analysis method of the echo signal for the purpose of the quantitative estimation of the liver fibrosis. On the assumption that the echo signal from fibrotic liver is composed of reflected signals from normal and fibrotic tissues, we proposed the model in which the amplitude distribution of the echo signal is expressed by combining two Rayleigh distributions. Using this model, we are able to obtain the quantity and stage of fibrotic degeneration of liver from statistics of the echo amplitude as an inverse problem, and presented the possibility of quantitative estimation of fibrosis liver. In this technique, it is important to know how much this model can express actual data. In this paper, we evaluate the accuracy of approximation of the amplitude distribution model for fibrotic liver. The Kullback Leibler (KL) divergence was used as an index of the accuracy of approximation of distribution. ROI set on the clinical image data was moved, and the accuracy of approximation on the entire image was evaluated. As a result, it became clear that the proposed model can be approximated from a normal liver to a cirrhotic liver when there are neither a blood vessel nor tissue boundaries.
Keyword (in Japanese) (See Japanese page) 
(in English) medical ultrasound / Rayleigh distribution / statistical analysis / quantitative diagnosis / diffuse liver disease / hepatitis fibrosis / /  
Reference Info. IEICE Tech. Rep., vol. 110, no. 419, US2010-113, pp. 7-12, Feb. 2011.
Paper # US2010-113 
Date of Issue 2011-02-14 (US) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
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All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee US  
Conference Date 2011-02-21 - 2011-02-21 
Place (in Japanese) (See Japanese page) 
Place (in English)  
Topics (in Japanese) (See Japanese page) 
Topics (in English) Acoustic Imaging, General, etc 
Paper Information
Registration To US 
Conference Code 2011-02-US 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Accuracy analysis of echo amplitude distribution model for fibrotic liver 
Sub Title (in English)  
Keyword(1) medical ultrasound  
Keyword(2) Rayleigh distribution  
Keyword(3) statistical analysis  
Keyword(4) quantitative diagnosis  
Keyword(5) diffuse liver disease  
Keyword(6) hepatitis fibrosis  
Keyword(7)  
Keyword(8)  
1st Author's Name Yu Igarashi  
1st Author's Affiliation Tokyo Institute of Technology (Tokyo Inst. of Tech.)
2nd Author's Name Tadashi Yamaguchi  
2nd Author's Affiliation Chiba University (Chiba Univ.)
3rd Author's Name Hiroyuki Hachiya  
3rd Author's Affiliation Tokyo Institute of Technology (Tokyo Inst. of Tech.)
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Speaker Author-1 
Date Time 2011-02-21 10:10:00 
Presentation Time 25 minutes 
Registration for US 
Paper # US2010-113 
Volume (vol) vol.110 
Number (no) no.419 
Page pp.7-12 
#Pages
Date of Issue 2011-02-14 (US) 


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