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Paper Abstract and Keywords
Presentation 2013-01-25 14:30
An approach to the haplotype inference using moment generating function
Shizuka Ono, Masato Inoue (Waseda Univ.) NLP2012-137 NC2012-127
Abstract (in Japanese) (See Japanese page) 
(in English) Haplotype inference is a statistical problem to separate mixed human genomic information into maternal and paternal haplotypes. Intensive studies for this problem have been dedicated to contribute individualized medicine. One of the most successful studies is a method using EM algorithm with Hardy-Weinberg assumption. Its accuracy is generally quite high, but it suffers from exponential calculation cost regarding the number of polymorphic sites because it does not utilize the sparsity of haplotype frequencies. In this report, focusing on a property of the haplotype inference, we introduce a new approach to estimation of haplotype frequencies. Specifically, we use moment generating function and sparse optimization technique. We also evaluate the accuracy of the method with artificial data.
Keyword (in Japanese) (See Japanese page) 
(in English) haplotype inference / moment generating function / sparse optimization / compressed sensing / / / /  
Reference Info. IEICE Tech. Rep., vol. 112, no. 390, NC2012-127, pp. 187-191, Jan. 2013.
Paper # NC2012-127 
Date of Issue 2013-01-17 (NLP, NC) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
and
reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF NLP2012-137 NC2012-127

Conference Information
Committee NC NLP  
Conference Date 2013-01-24 - 2013-01-25 
Place (in Japanese) (See Japanese page) 
Place (in English) Hokkaido University Centennial Memory Hall 
Topics (in Japanese) (See Japanese page) 
Topics (in English)  
Paper Information
Registration To NC 
Conference Code 2013-01-NC-NLP 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) An approach to the haplotype inference using moment generating function 
Sub Title (in English)  
Keyword(1) haplotype inference  
Keyword(2) moment generating function  
Keyword(3) sparse optimization  
Keyword(4) compressed sensing  
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1st Author's Name Shizuka Ono  
1st Author's Affiliation Waseda University (Waseda Univ.)
2nd Author's Name Masato Inoue  
2nd Author's Affiliation Waseda University (Waseda Univ.)
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Speaker Author-1 
Date Time 2013-01-25 14:30:00 
Presentation Time 20 minutes 
Registration for NC 
Paper # NLP2012-137, NC2012-127 
Volume (vol) vol.112 
Number (no) no.389(NLP), no.390(NC) 
Page pp.187-191 
#Pages 5 
Date of Issue 2013-01-17 (NLP, NC) 

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