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Paper Abstract and Keywords
Presentation 2013-05-27 14:00
Development of adherent cell culture flask with acoustic window film for ultrasound exposure
Sakino Iwashiro, Akiko Watanabe, Masatsune Minai, Hiroyuki Nishimura, Shinichi Takeuchi (Toin Yokohama Univ.) US2013-9
Abstract (in Japanese) (See Japanese page) 
(in English) In recent years, the transscanial brain tumor treatment system by High Intensity Focused Ultrasound (HIFU) has been studied.This treatment has the advantage that it is minimally invasive and it can be applied repeatedly unlike radiotherapy.However, when brain tumor cells are coagulated and are necrotized with this treatment system, the surrounding normal brain tissue may be affected by the necrosis.Therefore, we have been considering trying to use apoptosis induction into brain tumor cells by ultrasound exposure for ultrasound brain tumor treatment system.When the commercial polystyrene cell culture flasks with thickness of about 2mm were employed as containers of target brain tumor cells exposed to ultrasound, there was a problem that ultrasound energy was reflected at the surface of the flask with different specific acoustic impedance from water outside of the flask and culture medium in the flask, but did not reach the cells sufficiently.Therefore, we prepared the original cell culture flasks with acoustic window for ultrasound exposure and cell culture.This report describes the study on development of cell culture flask with a thin polymer film acoustic window for culture of adherent cell and ultrasound irradiation.
Keyword (in Japanese) (See Japanese page) 
(in English) brain tumor / adherent cell / cell culture flask / acoustic window film / apoptosis / / /  
Reference Info. IEICE Tech. Rep., vol. 113, no. 68, US2013-9, pp. 7-12, May 2013.
Paper # US2013-9 
Date of Issue 2013-05-20 (US) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
and
reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF US2013-9

Conference Information
Committee US  
Conference Date 2013-05-27 - 2013-05-27 
Place (in Japanese) (See Japanese page) 
Place (in English) Kikai-Shinko-Kaikan Bldg. 
Topics (in Japanese) (See Japanese page) 
Topics (in English) General 
Paper Information
Registration To US 
Conference Code 2013-05-US 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Development of adherent cell culture flask with acoustic window film for ultrasound exposure 
Sub Title (in English)  
Keyword(1) brain tumor  
Keyword(2) adherent cell  
Keyword(3) cell culture flask  
Keyword(4) acoustic window film  
Keyword(5) apoptosis  
Keyword(6)  
Keyword(7)  
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1st Author's Name Sakino Iwashiro  
1st Author's Affiliation Toin Yokohama University (Toin Yokohama Univ.)
2nd Author's Name Akiko Watanabe  
2nd Author's Affiliation Toin Yokohama University (Toin Yokohama Univ.)
3rd Author's Name Masatsune Minai  
3rd Author's Affiliation Toin Yokohama University (Toin Yokohama Univ.)
4th Author's Name Hiroyuki Nishimura  
4th Author's Affiliation Toin Yokohama University (Toin Yokohama Univ.)
5th Author's Name Shinichi Takeuchi  
5th Author's Affiliation Toin Yokohama University (Toin Yokohama Univ.)
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Speaker Author-1 
Date Time 2013-05-27 14:00:00 
Presentation Time 30 minutes 
Registration for US 
Paper # US2013-9 
Volume (vol) vol.113 
Number (no) no.68 
Page pp.7-12 
#Pages 6 
Date of Issue 2013-05-20 (US) 

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