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Paper Abstract and Keywords
Presentation 2013-07-18 15:55
Quantitative Analysis of Amyloid Deposits in PET/CT Images
Kei Sasaki (Yamagata Univ./National Center of Neurology and Psychiatry), Norihide Maikusa (National Center of Neurology and Psychiatry), Tetsuya Yuasa (Yamagata Univ.), Etsuko Imabayashi (Tokyo Metropolitan Geriatric Hospital), Hiroshi Matsuda (National Center of Neurology and Psychiatry) MI2013-28
Abstract (in Japanese) (See Japanese page) 
(in English) For early diagnosis of Alzheimer’s disease (AD), it is effective to quantitatively evaluate deposits of amyloid into gray matter, which can be estimated from an Amyloid PET (Positron Emission Tomography) image. However, the deposit quantity in gray matter tends to be underestimated, which is caused by partial volume effect (PVE) due to the lower spatial resolution of PET. This study proposes a method to correct the PVE of a PET image using an X-ray CT image, where they are simultaneously acquired by PET/CT, and to restore the quantitative property in evaluating deposits of amyloid. We show the effectiveness by comparing the result based on an X-ray CT image with that based on an MRI image, obtained from a healthy volunteer.
Keyword (in Japanese) (See Japanese page) 
(in English) PET/CT / Alzheimer’s disease / partial volume effect / amyloid imaging / / / /  
Reference Info. IEICE Tech. Rep., vol. 113, no. 146, MI2013-28, pp. 49-53, July 2013.
Paper # MI2013-28 
Date of Issue 2013-07-11 (MI) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
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reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee MI  
Conference Date 2013-07-18 - 2013-07-19 
Place (in Japanese) (See Japanese page) 
Place (in English)  
Topics (in Japanese) (See Japanese page) 
Topics (in English)  
Paper Information
Registration To MI 
Conference Code 2013-07-MI 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Quantitative Analysis of Amyloid Deposits in PET/CT Images 
Sub Title (in English)  
Keyword(1) PET/CT  
Keyword(2) Alzheimer’s disease  
Keyword(3) partial volume effect  
Keyword(4) amyloid imaging  
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1st Author's Name Kei Sasaki  
1st Author's Affiliation Yamagata University/National Center of Neurology and Psychiatry (Yamagata Univ./National Center of Neurology and Psychiatry)
2nd Author's Name Norihide Maikusa  
2nd Author's Affiliation National Center of Neurology and Psychiatry (National Center of Neurology and Psychiatry)
3rd Author's Name Tetsuya Yuasa  
3rd Author's Affiliation Yamagata University (Yamagata Univ.)
4th Author's Name Etsuko Imabayashi  
4th Author's Affiliation Tokyo Metropolitan Geriatric Hospital (Tokyo Metropolitan Geriatric Hospital)
5th Author's Name Hiroshi Matsuda  
5th Author's Affiliation National Center of Neurology and Psychiatry (National Center of Neurology and Psychiatry)
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Speaker Author-1 
Date Time 2013-07-18 15:55:00 
Presentation Time 30 minutes 
Registration for MI 
Paper # MI2013-28 
Volume (vol) vol.113 
Number (no) no.146 
Page pp.49-53 
#Pages 5 
Date of Issue 2013-07-11 (MI) 

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