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Paper Abstract and Keywords
Presentation 2014-01-27 10:50
Ultrasound bubble filter for an extracorporeal circulation and effect on blood
Koji Mino, Masato Imura, Daisuke Koyama (Doshisha Univ.), Shigeki Kawarabata, Masafumi Sato (JMS), Yoshiaki Watanabe (Doshisha Univ.) US2013-83
Abstract (in Japanese) (See Japanese page) 
(in English) An ultrasound bubble filter for an extracorporeal circulation which has no mesh structure was developed. In this report, the effect of ultrasound on hemolysis and the filtering characteristics of the flowing microbubbles are investigated at several driving frequencies. The hemolysis was evaluated by free hemoglobin (FHb) with SLS-hemoglobin method. Bovine blood of 120 mL was exposed to ultrasound at the frequencies of 1 MHz, 500 and 27 kHz for 15 minutes, and the FHb were 641.6, 2575 and 8903 mg/dL, respectively. The hemolysis could be inhibited with higher driving frequency. An ultrasound bubble filter with the resonance frequency of 1 MHz was designed. The filter consists of an aluminum cylinder (length: 130 mm; inner diameter: 30 mm) and has one inlet at the center of the side and two outlets at both ends. The filtering characteristics were investigated through a circulation system using bovine blood with the flow of 5.0 l/min. The air is injected and fragmented into about 40-m-diameter microbubbles at the centrifugal pump. As a result, 99.1% of microbubbles was filtered at 250 kPa. In the case of bovine blood of 400 mL and the flow of 5.0 l/min, the FHb was 1277 mg/dL for 60 minutes. These results imply that the high filtering ability and low hemolysis are trade-off.
Keyword (in Japanese) (See Japanese page) 
(in English) Extracorporeal circulation / Arterial filter / Acoustic radiation force / Ultrasonic manipulation / Hemolysis / / /  
Reference Info. IEICE Tech. Rep., vol. 113, no. 412, US2013-83, pp. 9-14, Jan. 2014.
Paper # US2013-83 
Date of Issue 2014-01-20 (US) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
and
reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee EA US  
Conference Date 2014-01-27 - 2014-01-28 
Place (in Japanese) (See Japanese page) 
Place (in English) Kansai University, Centenary Memorial Hall 
Topics (in Japanese) (See Japanese page) 
Topics (in English) [Joint Meeting on Acoustics and Ultrasonics Subsociety] Engineering/Electro Acoustics, Ultrasonic and Underwater Acoustics，and Related Topics 
Paper Information
Registration To US 
Conference Code 2014-01-EA-US 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Ultrasound bubble filter for an extracorporeal circulation and effect on blood 
Sub Title (in English)  
Keyword(1) Extracorporeal circulation  
Keyword(2) Arterial filter  
Keyword(3) Acoustic radiation force  
Keyword(4) Ultrasonic manipulation  
Keyword(5) Hemolysis  
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Keyword(8)  
1st Author's Name Koji Mino  
1st Author's Affiliation Doshisha University (Doshisha Univ.)
2nd Author's Name Masato Imura  
2nd Author's Affiliation Doshisha University (Doshisha Univ.)
3rd Author's Name Daisuke Koyama  
3rd Author's Affiliation Doshisha University (Doshisha Univ.)
4th Author's Name Shigeki Kawarabata  
4th Author's Affiliation Central Research Laboratory, JMS Co., Ltd. (JMS)
5th Author's Name Masafumi Sato  
5th Author's Affiliation Central Research Laboratory, JMS Co., Ltd. (JMS)
6th Author's Name Yoshiaki Watanabe  
6th Author's Affiliation Doshisha University (Doshisha Univ.)
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Speaker Author-1 
Date Time 2014-01-27 10:50:00 
Presentation Time 25 minutes 
Registration for US 
Paper # US2013-83 
Volume (vol) vol.113 
Number (no) no.412 
Page pp.9-14 
#Pages 6 
Date of Issue 2014-01-20 (US) 

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