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Paper Abstract and Keywords
Presentation 2015-01-26 16:20
A study on the method of biological pacemaker creation based on the bifurcation analysis of a ventricular cell model with hyperpolarization-activated current introduced
Yoshiki Ogawa, Shinji Doi (Kyoto Univ.) NLP2014-125
Abstract (in Japanese) (See Japanese page) 
(in English) Biological pacemaker engineering is a new strategy to initiate pacemaker activity in non-pacemaking cells，and it is expected as an alternative to electronic pacemaker.
Since it is necessary for biological pacemaker engineering to understand the dynamics of various ion channels comprehensively, we use the mathematical cell model.
Hyperpolarization-activated current is important ionic current in the pacemaker activity of the sinoatrial node.
In this report, we analyze the bifurcation structure of a human ventricular cell model with this current introduced by varying conductances of ion channels, and examine the method to induce pacemaker activity in a quiescent cell.
Keyword (in Japanese) (See Japanese page) 
(in English) biological pacemaker engineering / ventricular cell model / bifurcation analysis / hyperpolarization-activated current / / / /  
Reference Info. IEICE Tech. Rep., vol. 114, no. 414, NLP2014-125, pp. 71-76, Jan. 2015.
Paper # NLP2014-125 
Date of Issue 2015-01-19 (NLP) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
and
reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF NLP2014-125

Conference Information
Committee NLP  
Conference Date 2015-01-26 - 2015-01-27 
Place (in Japanese) (See Japanese page) 
Place (in English) Compal Hall 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Nonlinear Problems, etc. 
Paper Information
Registration To NLP 
Conference Code 2015-01-NLP 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) A study on the method of biological pacemaker creation based on the bifurcation analysis of a ventricular cell model with hyperpolarization-activated current introduced 
Sub Title (in English)  
Keyword(1) biological pacemaker engineering  
Keyword(2) ventricular cell model  
Keyword(3) bifurcation analysis  
Keyword(4) hyperpolarization-activated current  
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1st Author's Name Yoshiki Ogawa  
1st Author's Affiliation Kyoto University (Kyoto Univ.)
2nd Author's Name Shinji Doi  
2nd Author's Affiliation Kyoto University (Kyoto Univ.)
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Speaker Author-1 
Date Time 2015-01-26 16:20:00 
Presentation Time 25 minutes 
Registration for NLP 
Paper # NLP2014-125 
Volume (vol) vol.114 
Number (no) no.414 
Page pp.71-76 
#Pages 6 
Date of Issue 2015-01-19 (NLP) 

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