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Paper Abstract and Keywords
Presentation 2015-03-17 13:30
Development of an Automated Fiber-tracking Method using MR Diffusion Tensor Imaging and Parcellation Map
Hodaka Miki, Tetsuo Kobayashi (Kyoto Univ) MBE2014-135 NC2014-86
Abstract (in Japanese) (See Japanese page) 
(in English) 【Purpose】Recently, about 1% of peoples around the world suffer schizophrenia, and the number of schizophrenic patients thought to be increasing in the future. Therefore, it is necessary to analyze cerebral white matter integrity using nerve fiber tractography and quantitatively evaluate schizophrenia. In this study, to clarify physical fiber connections associated with disease specific neuronal circuits, we developed an automated fiber tracking method using MR-DTI.【Method】Based on a parcellation map separating 54 regions of the white matter, we developed the following two methods. The first method automatically sets region of interest（ROI）, whereas the second one automatically rotates the starting and ending surfaces of fiber tracking. These methods were verified using simulation data which referred to MR-DTI of 18 healthy controls. 【Result】First, the newly developed methods could automatically set ROIs in wide regions where nerve fivers could be tracked sufficiently long. Secondly, the starting and ending surfaces of fiber tracking could accurately rotated along the running direction of fibers. Finally, streamlines of fiber tracking were confirmed to run along the first component of eigenvectors of simulation data. 【Conclusion】These data demonstrate that the automated fiber tracking methods were feasible and may quantitatively evaluate schizophrenia based on parameters obtained by streamlines of fiber tracking.
Keyword (in Japanese) (See Japanese page) 
(in English) Schizophrenia / Magnetic Resonance Imaging (MRI) / Magnetic Resonance Diffusion Tensor Imaging (MR-DTI) / Parcellation Map / Tractography / / /  
Reference Info. IEICE Tech. Rep., vol. 114, no. 514, MBE2014-135, pp. 105-110, March 2015.
Paper # MBE2014-135 
Date of Issue 2015-03-09 (MBE, NC) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
and
reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF MBE2014-135 NC2014-86

Conference Information
Committee NC MBE  
Conference Date 2015-03-16 - 2015-03-17 
Place (in Japanese) (See Japanese page) 
Place (in English) Tamagawa University 
Topics (in Japanese) (See Japanese page) 
Topics (in English) ME, etc 
Paper Information
Registration To MBE 
Conference Code 2015-03-NC-MBE 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Development of an Automated Fiber-tracking Method using MR Diffusion Tensor Imaging and Parcellation Map 
Sub Title (in English)  
Keyword(1) Schizophrenia  
Keyword(2) Magnetic Resonance Imaging (MRI)  
Keyword(3) Magnetic Resonance Diffusion Tensor Imaging (MR-DTI)  
Keyword(4) Parcellation Map  
Keyword(5) Tractography  
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Keyword(7)  
Keyword(8)  
1st Author's Name Hodaka Miki  
1st Author's Affiliation Kyoto University (Kyoto Univ)
2nd Author's Name Tetsuo Kobayashi  
2nd Author's Affiliation Kyoto University (Kyoto Univ)
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Speaker Author-1 
Date Time 2015-03-17 13:30:00 
Presentation Time 25 minutes 
Registration for MBE 
Paper # MBE2014-135, NC2014-86 
Volume (vol) vol.114 
Number (no) no.514(MBE), no.515(NC) 
Page pp.105-110 
#Pages 6 
Date of Issue 2015-03-09 (MBE, NC) 

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