Positive emotional activities including gabbing and laughing have been demonstrated to provide various neurological and physiological effects, hence, their clinical implementations are expected. We found that such activities enhance both deep-brain activity index (DBA) derived from EEG occipital alpha power fluctuations and heart-rate variability in the very-low fre-quency range of below 0.04Hz, which is supposed to be related to the hypothalamic activity. We further found that prosodic dysfunctions of an RHD patient were relieved under such positive activities.