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Paper Abstract and Keywords
Presentation 2016-01-20 10:08
Quantification method of individual macrophage dynamics in living mouse brain using 11.7T time lapse MR images
Atsuki Tashita, Syoji Kobashi (Univ of Hyogo), Yuki Mori (Osaka Univ), Seichi Goshi (Kogakuin Univ), Masakazu Morimoto, Satoru Aikawa (Univ of Hyogo), Yoshichika Yoshioka (Osaka Univ), Yutaka Hata (Univ of Hyogo) MI2015-115
Abstract (in Japanese) (See Japanese page) 
(in English) It is difficult to directly observe immune cells of living organs without any invasion. Macrophage is the representative cell of immune cells. Recently, our study enables us to visualize individual macrophage in living mouse brain using 11.7 T magnetic resonance imaging (MRI) scanner. This paper proposes a dynamics quantification method for MR images to track the cellular dynamics. The method consists of noise reduction method and macrophage tracking method. The method has been applied to MRI data from model mice of brain stroke. The results showed that the tracking accuracy of the macrophages was improved by the noise reduction method. We also calculate the number of macrophages and the average velocity from each cerebral hemisphere.
Keyword (in Japanese) (See Japanese page) 
(in English) Macrophage / Magnetic Resonance Imaging / Immune system / Hungarian algorithm / Multiple object tracking / Noise reduction / /  
Reference Info. IEICE Tech. Rep., vol. 115, no. 401, MI2015-115, pp. 205-210, Jan. 2016.
Paper # MI2015-115 
Date of Issue 2016-01-12 (MI) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
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reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee MI  
Conference Date 2016-01-19 - 2016-01-20 
Place (in Japanese) (See Japanese page) 
Place (in English) Bunka Tenbusu Kan 
Topics (in Japanese) (See Japanese page) 
Topics (in English) General topics in medical imaging 
Paper Information
Registration To MI 
Conference Code 2016-01-MI 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Quantification method of individual macrophage dynamics in living mouse brain using 11.7T time lapse MR images 
Sub Title (in English)  
Keyword(1) Macrophage  
Keyword(2) Magnetic Resonance Imaging  
Keyword(3) Immune system  
Keyword(4) Hungarian algorithm  
Keyword(5) Multiple object tracking  
Keyword(6) Noise reduction  
Keyword(7)  
Keyword(8)  
1st Author's Name Atsuki Tashita  
1st Author's Affiliation University of Hyogo (Univ of Hyogo)
2nd Author's Name Syoji Kobashi  
2nd Author's Affiliation University of Hyogo (Univ of Hyogo)
3rd Author's Name Yuki Mori  
3rd Author's Affiliation Osaka University (Osaka Univ)
4th Author's Name Seichi Goshi  
4th Author's Affiliation Kogakuin University (Kogakuin Univ)
5th Author's Name Masakazu Morimoto  
5th Author's Affiliation University of Hyogo (Univ of Hyogo)
6th Author's Name Satoru Aikawa  
6th Author's Affiliation University of Hyogo (Univ of Hyogo)
7th Author's Name Yoshichika Yoshioka  
7th Author's Affiliation Osaka University (Osaka Univ)
8th Author's Name Yutaka Hata  
8th Author's Affiliation University of Hyogo (Univ of Hyogo)
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Speaker Author-1 
Date Time 2016-01-20 10:08:00 
Presentation Time 12 minutes 
Registration for MI 
Paper # MI2015-115 
Volume (vol) vol.115 
Number (no) no.401 
Page pp.205-210 
#Pages 6 
Date of Issue 2016-01-12 (MI) 

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