| Paper Abstract and Keywords |
| Presentation |
2016-03-22 14:55
Possible role of angiogenesis in transient post-ischemic hyperperfusion in rats Kazuhiro Nakamura, Junko Kawamura, Yasushi Kondoh, Hajime MIyata, Toshibumi Kinoshita (Akita Noken) MBE2015-112 |
| Abstract |
(in Japanese) |
(See Japanese page) |
| (in English) |
Post-ischemic hyperperfusion was observed a few days after transient middle cerebral artery occlusion (tMCAO) . We assume the hyperperfusion was caused by angiogenesis occurred after tMCAO. To evaluate the hypothesis, we administrated angiogenesis inhibitor SU5416 and evaluated cerebral blood flow in 48 hours after MCAO with continuous arterial spin labeling in MRI. Post-ischmeic hyperperfusion in caudate nucleus was statistically reduced in SU5416 administration compared to control group. Dilated arteries and vessel endothelial cell proliferation in caudate nucleus was inhibited in pathological preparation. The post-ischemic hyperperfusion might be related to the angiogenesis. |
| Keyword |
(in Japanese) |
(See Japanese page) |
| (in English) |
CBF / MRI / Stroke / / / / / |
| Reference Info. |
IEICE Tech. Rep., vol. 115, no. 513, MBE2015-112, pp. 51-54, March 2016. |
| Paper # |
MBE2015-112 |
| Date of Issue |
2016-03-15 (MBE) |
| ISSN |
Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
| Download PDF |
MBE2015-112 |
| Conference Information |
| Committee |
MBE NC |
| Conference Date |
2016-03-22 - 2016-03-23 |
| Place (in Japanese) |
(See Japanese page) |
| Place (in English) |
Tamagawa University |
| Topics (in Japanese) |
(See Japanese page) |
| Topics (in English) |
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| Paper Information |
| Registration To |
MBE |
| Conference Code |
2016-03-MBE-NC |
| Language |
Japanese |
| Title (in Japanese) |
(See Japanese page) |
| Sub Title (in Japanese) |
(See Japanese page) |
| Title (in English) |
Possible role of angiogenesis in transient post-ischemic hyperperfusion in rats |
| Sub Title (in English) |
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| Keyword(1) |
CBF |
| Keyword(2) |
MRI |
| Keyword(3) |
Stroke |
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| 1st Author's Name |
Kazuhiro Nakamura |
| 1st Author's Affiliation |
Akita Research Institute for Brain and Blood Vessels (Akita Noken) |
| 2nd Author's Name |
Junko Kawamura |
| 2nd Author's Affiliation |
Akita Research Institute for Brain and Blood Vessels (Akita Noken) |
| 3rd Author's Name |
Yasushi Kondoh |
| 3rd Author's Affiliation |
Akita Research Institute for Brain and Blood Vessels (Akita Noken) |
| 4th Author's Name |
Hajime MIyata |
| 4th Author's Affiliation |
Akita Research Institute for Brain and Blood Vessels (Akita Noken) |
| 5th Author's Name |
Toshibumi Kinoshita |
| 5th Author's Affiliation |
Akita Research Institute for Brain and Blood Vessels (Akita Noken) |
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| Speaker |
Author-1 |
| Date Time |
2016-03-22 14:55:00 |
| Presentation Time |
25 minutes |
| Registration for |
MBE |
| Paper # |
MBE2015-112 |
| Volume (vol) |
vol.115 |
| Number (no) |
no.513 |
| Page |
pp.51-54 |
| #Pages |
4 |
| Date of Issue |
2016-03-15 (MBE) |