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Paper Abstract and Keywords
Presentation 2017-10-07 14:30
[Invited Talk] Electronic devices and physiological studies for visual prostheses with intra-cortical micro-stimulation
Yuki Hayashida (Osaka Univ.) NC2017-22-1
Abstract (in Japanese) (See Japanese page) 
(in English) With the recent development of integration technology, neural prosthetic treatments for various brain dysfunctions with electronic devices have been considered to become a reality. We have been conducting researches on the visual prosthesis with intra-cortical micro-stimulation, which gives electrical pattern stimulation to the cerebral visual cortex of the patients with acquired blindness to artificially induce the perception of light spots patterns. In late 1960s, indeed, chronic clinical trials of a visual prosthesis with cortical surface stimulation were conducted. However, the stimulus current of milli-ampere order, and the stimulating electrode of milli-meter size, used in such a surface type presented various limitations of safety and technical problems, and thus of realizing a prosthetic vision. In the 1990's, a possible usefulness of the intra-cortical micro-stimulation with the stimulus current of micro-ampere order, and needle-shaped micron-sized electrodes inserted in the cerebral cortex, was demonstrated by animal experiments and a few clinical trials, although this type of prosthesis also facing many challenges. Recently, we have developed a prototype of the electronic device system that enables multi-site microstimulation of more than 1000 channels and operation by wireless power/signal transmission. This system is very practical enough to meet the quantitative specification required for intra-cortical micro-stimulation, and is extremely useful for preclinical experimental studies with experimental animals. In this presentation, I would like to introduce the system development and basic research with the physiological experiments.
Keyword (in Japanese) (See Japanese page) 
(in English) Visual prosthesis / Intra-cortical micro-stimulation / Electronics device / Physiological experiment / / / /  
Reference Info. IEICE Tech. Rep., vol. 117, no. 231, NC2017-22-1, Oct. 2017.
Paper # NC2017-22-1 
Date of Issue 2017-09-30 (NC) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
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All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee MBE NC  
Conference Date 2017-10-07 - 2017-10-07 
Place (in Japanese) (See Japanese page) 
Place (in English) Osaka Electro-Communication University 
Topics (in Japanese) (See Japanese page) 
Topics (in English) ME, general 
Paper Information
Registration To NC 
Conference Code 2017-10-MBE-NC 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Electronic devices and physiological studies for visual prostheses with intra-cortical micro-stimulation 
Sub Title (in English)  
Keyword(1) Visual prosthesis  
Keyword(2) Intra-cortical micro-stimulation  
Keyword(3) Electronics device  
Keyword(4) Physiological experiment  
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1st Author's Name Yuki Hayashida  
1st Author's Affiliation Osaka University (Osaka Univ.)
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Speaker Author-1 
Date Time 2017-10-07 14:30:00 
Presentation Time 60 minutes 
Registration for NC 
Paper # NC2017-22-1 
Volume (vol) vol.117 
Number (no) no.231 
Page  
#Pages
Date of Issue 2017-09-30 (NC) 


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