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Paper Abstract and Keywords
Presentation 2017-10-07 10:20
Changes in light response characteristics of mouse retinal ganglion cells depending on background light
Kenji Shiota, Yuki Naruto, Yuki Kashiwagi, Naofumi Suemats, Tetsuya Yagi, Yuki Hayashida (Osaka Univ.) MBE2017-43
Abstract (in Japanese) (See Japanese page) 
(in English) In recent years, the mouse has attracted attention as an experimental animal for studying retinal neuronal circuits. And it has been shown that the photosensitivity and the temporal filter characteristics of the photoresponse of the ganglion cells in the cone pathway are comparable to those of the primate retina. However, it is not fully understood how spike firing characteristics in response to step light stimulation of these output cells can change depending on the visual environment such as background light. In this study, we investigated by electrophysiological experiments whether spike firing response of mouse retinal ganglion cells can change according to the difference of two background light conditions between mesopic and photopic vision. In the experiments, time-series spike data were recorded from the isolated retina tissue using a planar multielectrode array. The single spike units were separated by the principal component analysis and cluster analysis, and then, were classified into different subtypes based on characteristics of the response to step light stimuli. As a result, in some subtypes, the photoresponse was disappeared by the adaptation from mesopic to photopic vision, but in other cases, a qualitative change in the response characteristics was not observed.
Keyword (in Japanese) (See Japanese page) 
(in English) mouse retinal ganglion cell / step light stimulus / background light / mesopic and photopic vision / / / /  
Reference Info. IEICE Tech. Rep., vol. 117, no. 230, MBE2017-43, pp. 11-16, Oct. 2017.
Paper # MBE2017-43 
Date of Issue 2017-09-30 (MBE) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
and
reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee MBE NC  
Conference Date 2017-10-07 - 2017-10-07 
Place (in Japanese) (See Japanese page) 
Place (in English) Osaka Electro-Communication University 
Topics (in Japanese) (See Japanese page) 
Topics (in English) ME, general 
Paper Information
Registration To MBE 
Conference Code 2017-10-MBE-NC 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Changes in light response characteristics of mouse retinal ganglion cells depending on background light 
Sub Title (in English)  
Keyword(1) mouse retinal ganglion cell  
Keyword(2) step light stimulus  
Keyword(3) background light  
Keyword(4) mesopic and photopic vision  
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1st Author's Name Kenji Shiota  
1st Author's Affiliation Osaka University (Osaka Univ.)
2nd Author's Name Yuki Naruto  
2nd Author's Affiliation Osaka University (Osaka Univ.)
3rd Author's Name Yuki Kashiwagi  
3rd Author's Affiliation Osaka University (Osaka Univ.)
4th Author's Name Naofumi Suemats  
4th Author's Affiliation Osaka University (Osaka Univ.)
5th Author's Name Tetsuya Yagi  
5th Author's Affiliation Osaka University (Osaka Univ.)
6th Author's Name Yuki Hayashida  
6th Author's Affiliation Osaka University (Osaka Univ.)
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Speaker Author-1 
Date Time 2017-10-07 10:20:00 
Presentation Time 25 minutes 
Registration for MBE 
Paper # MBE2017-43 
Volume (vol) vol.117 
Number (no) no.230 
Page pp.11-16 
#Pages 6 
Date of Issue 2017-09-30 (MBE) 

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