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Paper Abstract and Keywords
Presentation 2018-01-31 14:05
Liquid-Phase Detection of Biomaterial Using Magnetic Markers
Yoshitsugu Takafuji, Kouta Irie, Kazuki Akiyoshi, Teruyoshi Sasayama, Takashi Yoshida, Keizi Enpuku (Kyushu Univ.) SCE2017-39
Abstract (in Japanese) (See Japanese page) 
(in English) We have been developing a liquid-phase immunoassay using magnetic markers and a superconducting quantum interference device (SQUID). In this method, bound and free markers are magnetically differentiated by using the Brownian relaxation of the free markers. Hence, the time consuming washing process that is needed in the conventional optical method for Bound/Free (B/F) separation can be eliminated. Using the method, we demonstrated a detection of C-reactive protein (CRP). We obtained good correlation between the detected signal flux and the concentration of CRP. The minimum detectable concentration was 1 pg/mL. Since the present sensitivity is limited by the blank signal caused by the aggregation of free markers, much improvement will be possible if this problem is solved.
Keyword (in Japanese) (See Japanese page) 
(in English) CRP / Brownian Relaxation / Immunoassay / Magnetic Marker / HTS SQUID / / /  
Reference Info. IEICE Tech. Rep., vol. 117, no. 428, SCE2017-39, pp. 45-50, Jan. 2018.
Paper # SCE2017-39 
Date of Issue 2018-01-24 (SCE) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
and
reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF SCE2017-39

Conference Information
Committee SCE  
Conference Date 2018-01-31 - 2018-01-31 
Place (in Japanese) (See Japanese page) 
Place (in English) Kikai-Shinko-Kaikan Bldg. 
Topics (in Japanese) (See Japanese page) 
Topics (in English) SQUID, high frequency, sensing technologies and their applications, etc. 
Paper Information
Registration To SCE 
Conference Code 2018-01-SCE 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Liquid-Phase Detection of Biomaterial Using Magnetic Markers 
Sub Title (in English)  
Keyword(1) CRP  
Keyword(2) Brownian Relaxation  
Keyword(3) Immunoassay  
Keyword(4) Magnetic Marker  
Keyword(5) HTS SQUID  
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Keyword(7)  
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1st Author's Name Yoshitsugu Takafuji  
1st Author's Affiliation Kyushu University (Kyushu Univ.)
2nd Author's Name Kouta Irie  
2nd Author's Affiliation Kyushu University (Kyushu Univ.)
3rd Author's Name Kazuki Akiyoshi  
3rd Author's Affiliation Kyushu University (Kyushu Univ.)
4th Author's Name Teruyoshi Sasayama  
4th Author's Affiliation Kyushu University (Kyushu Univ.)
5th Author's Name Takashi Yoshida  
5th Author's Affiliation Kyushu University (Kyushu Univ.)
6th Author's Name Keizi Enpuku  
6th Author's Affiliation Kyushu University (Kyushu Univ.)
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Speaker Author-1 
Date Time 2018-01-31 14:05:00 
Presentation Time 25 minutes 
Registration for SCE 
Paper # SCE2017-39 
Volume (vol) vol.117 
Number (no) no.428 
Page pp.45-50 
#Pages 6 
Date of Issue 2018-01-24 (SCE) 

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