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| Presentation | 2018-02-19 14:55 Multiscale Analysis of Skin Tissues in Clinical Study and Verification by Echo Simulation Masaaki Omura, Kenji Yoshida, Tamaki Honda, Shinsuke Akita, Ichiro Manabe, Tadashi Yamaguchi (Chiba Univ.)  US2017-116 |
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| Abstract | (in Japanese) | (See Japanese page) |
| (in English) | The goal of this study is to develop a quantitative ultrasound (QUS) method for diagnosing skin fibrosis or inflammation at the early stage of lymphedema. In this report, we characterized ex-vivo normal skin (n=3) and lymphedema skin (n=1) samples. RF echo signals were acquired using a self-made ultrasonic scanner with a 15 MHz and 25 MHz single element concave transducer. Moreover, we applied the signal analysis method using the echo amplitude envelope and the backscatter coefficient (BSC) to assess the conditions of collagen fibers. QUS parameters were clustering parameter $mu$ and diffuse to total signal power ratio parameter 1/($kappa$+1) of Homodyned-K distribution, and integrated BSC (IB) that indicates the intensity of backscattered echo signals. The median (25-75 percentiles) of calculated QUS parameters with 25 MHz transducer is below: $mu$ = 0.71 (0.43-1.16), IB = 4.32 (2.20-10.3)×10^{-3 }sr^{-1} mm^{-1} in the normal skin, and $mu$ = 2.03 (1.32-2.89), IB = 13.0 (6.49-23.4)×10^{-3 }sr^{-1} mm^{-1} in the lymphedema skin. It is considered that the number density of collagen fibers in the lymphedema dermis is higher, and its backscattered signal is more hyperechoic than normal dermis tissues due to skin fibrosis. This result in lymphedema skin was verified by computer simulation reflecting high number density with collagen fibers. | |
| Keyword | (in Japanese) | (See Japanese page) |
| (in English) | Tissue Characterization / Multiscale / Echo Signal Analysis Method / Simulation / Skin Tissues / / / | |
| Reference Info. | IEICE Tech. Rep., vol. 117, no. 441, US2017-116, pp. 25-30, Feb. 2018. | |
| Paper # | US2017-116 | |
| Date of Issue | 2018-02-12 (US) | |
| ISSN | Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 | |
| Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) | |
| Download PDF | US2017-116 |
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| Conference Information | |
| Committee | US |
| Conference Date | 2018-02-19 - 2018-02-19 |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Paper Information | |
| Registration To | US |
| Conference Code | 2018-02-US |
| Language | Japanese |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Multiscale Analysis of Skin Tissues in Clinical Study and Verification by Echo Simulation |
| Sub Title (in English) | |
| Keyword(1) | Tissue Characterization |
| Keyword(2) | Multiscale |
| Keyword(3) | Echo Signal Analysis Method |
| Keyword(4) | Simulation |
| Keyword(5) | Skin Tissues |
| Keyword(6) | |
| Keyword(7) | |
| Keyword(8) | |
| 1st Author's Name | Masaaki Omura |
| 1st Author's Affiliation | Chiba University (Chiba Univ.) |
| 2nd Author's Name | Kenji Yoshida |
| 2nd Author's Affiliation | Chiba University (Chiba Univ.) |
| 3rd Author's Name | Tamaki Honda |
| 3rd Author's Affiliation | Chiba University (Chiba Univ.) |
| 4th Author's Name | Shinsuke Akita |
| 4th Author's Affiliation | Chiba University (Chiba Univ.) |
| 5th Author's Name | Ichiro Manabe |
| 5th Author's Affiliation | Chiba University (Chiba Univ.) |
| 6th Author's Name | Tadashi Yamaguchi |
| 6th Author's Affiliation | Chiba University (Chiba Univ.) |
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| Speaker | Author-1 |
| Date Time | 2018-02-19 14:55:00 |
| Presentation Time | 25 minutes |
| Registration for | US |
| Paper # | US2017-116 |
| Volume (vol) | vol.117 |
| Number (no) | no.441 |
| Page | pp.25-30 |
| #Pages | 6 |
| Date of Issue | 2018-02-12 (US) |
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