Paper Abstract and Keywords |
Presentation |
2020-10-29 14:20
Analysis of the drift-diffusion properties in the mouse brain parenchyma by the functional integrative optical imaging method Akihisa Takahashi, Kenya Tanaka, Mitsuyuki Nakao, Norihiro Katayama (Tohoku Univ) MBE2020-17 |
Abstract |
(in Japanese) |
(See Japanese page) |
(in English) |
Recently, it has been found that the vertebrate brain has a unique waste clearance pathway called the glymphatic system. One of the unsolved problems of the system is whether the cerebrospinal fluid (CSF) flows in a constant direction or not in the brain parenchyma. To address this issue, we analyzed the diffusion property of the brain by the functional integrative optical imaging (fIOI) method. We measured the diffusion of fluorescent molecules injected in the brain parenchyma and analyzed time-lapse images of the fluoresce. It was found that the diffusion drifted toward a constant direction. The result supports the existence of the constant flow of the CSF in the brain parenchyma. |
Keyword |
(in Japanese) |
(See Japanese page) |
(in English) |
Glymphatic System / extracellular space (ECS) / Cerebrospinal fluid (CSF) / / / / / |
Reference Info. |
IEICE Tech. Rep., vol. 120, no. 215, MBE2020-17, pp. 23-26, Oct. 2020. |
Paper # |
MBE2020-17 |
Date of Issue |
2020-10-22 (MBE) |
ISSN |
Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
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MBE2020-17 |
Conference Information |
Committee |
MBE NC NLP CAS |
Conference Date |
2020-10-29 - 2020-10-30 |
Place (in Japanese) |
(See Japanese page) |
Place (in English) |
Online |
Topics (in Japanese) |
(See Japanese page) |
Topics (in English) |
ME,NC,CAS,NLP |
Paper Information |
Registration To |
MBE |
Conference Code |
2020-10-MBE-NC-NLP-CAS |
Language |
Japanese |
Title (in Japanese) |
(See Japanese page) |
Sub Title (in Japanese) |
(See Japanese page) |
Title (in English) |
Analysis of the drift-diffusion properties in the mouse brain parenchyma by the functional integrative optical imaging method |
Sub Title (in English) |
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Keyword(1) |
Glymphatic System |
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extracellular space (ECS) |
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Cerebrospinal fluid (CSF) |
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1st Author's Name |
Akihisa Takahashi |
1st Author's Affiliation |
Tohoku University (Tohoku Univ) |
2nd Author's Name |
Kenya Tanaka |
2nd Author's Affiliation |
Tohoku University (Tohoku Univ) |
3rd Author's Name |
Mitsuyuki Nakao |
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Tohoku University (Tohoku Univ) |
4th Author's Name |
Norihiro Katayama |
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Tohoku University (Tohoku Univ) |
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Speaker |
Author-1 |
Date Time |
2020-10-29 14:20:00 |
Presentation Time |
25 minutes |
Registration for |
MBE |
Paper # |
MBE2020-17 |
Volume (vol) |
vol.120 |
Number (no) |
no.215 |
Page |
pp.23-26 |
#Pages |
4 |
Date of Issue |
2020-10-22 (MBE) |
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