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Paper Abstract and Keywords
Presentation 2021-01-22 15:55
The different patterns of epileptic discharges in rat hippocampal slices based on the frequency of high frequency oscillations
Toyohiro Sawada, Hirofumi Arai, Ryusei Maeda, Kiyohisa Natume (KIT) NLP2020-54
Abstract (in Japanese) (See Japanese page) 
(in English) Electroencephalogram (EEG) reflects brain states and is classified by kinds of frequency. Among them, ripple or high frequency oscillations (HFO) in the 100 Hz~500 Hz range can be recorded from healthy brain and also from pathological brain, for example from hippocampus. HFO can be a biomarker of epileptogenesis. In this study, we revealed that there were three kinds of epileptic discharges interictal (IID), preictal (PID) and ictal discharges (ID) with the application of proepileptic agents to rat hippocampal slices. The three patterns had different HFO frequencies and durations. Furthermore, in CA3 mini slice, IID and PID were induced, and ID could not be observed. These results suggest that IID and PID may be induced in the local network in CA3, and ID is induced in the global network in CA3, CA1, and DG.
Keyword (in Japanese) (See Japanese page) 
(in English) Epilepsy / Hippocampus / High frequency oscillations / / / / /  
Reference Info. IEICE Tech. Rep., vol. 120, no. 330, NLP2020-54, pp. 76-81, Jan. 2021.
Paper # NLP2020-54 
Date of Issue 2021-01-14 (NLP) 
ISSN Online edition: ISSN 2432-6380
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All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee NC NLP  
Conference Date 2021-01-21 - 2021-01-22 
Place (in Japanese) (See Japanese page) 
Place (in English) Online 
Topics (in Japanese) (See Japanese page) 
Topics (in English) NC,NLP 
Paper Information
Registration To NLP 
Conference Code 2021-01-NC-NLP 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) The different patterns of epileptic discharges in rat hippocampal slices based on the frequency of high frequency oscillations 
Sub Title (in English)  
Keyword(1) Epilepsy  
Keyword(2) Hippocampus  
Keyword(3) High frequency oscillations  
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1st Author's Name Toyohiro Sawada  
1st Author's Affiliation Kyushu Institute of Technology (KIT)
2nd Author's Name Hirofumi Arai  
2nd Author's Affiliation Kyushu Institute of Technology (KIT)
3rd Author's Name Ryusei Maeda  
3rd Author's Affiliation Kyushu Institute of Technology (KIT)
4th Author's Name Kiyohisa Natume  
4th Author's Affiliation Kyushu Institute of Technology (KIT)
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Speaker Author-1 
Date Time 2021-01-22 15:55:00 
Presentation Time 25 minutes 
Registration for NLP 
Paper # NLP2020-54 
Volume (vol) vol.120 
Number (no) no.330 
Page pp.76-81 
#Pages
Date of Issue 2021-01-14 (NLP) 


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