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| Presentation | 2023-03-17 16:05 Development of a low-stress light stimulation device for daily Alzheimer's disease treatment Yuki Yamaoka, Monica Perusquia-Hernandez, Naoya Isoyama, Hideaki Uchiyama, Kiyoshi Kiyokawa (NAIST), Takeshi Morimoto (OU)  IMQ2022-90 IE2022-167 MVE2022-120 |
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| Abstract | (in Japanese) | (See Japanese page) |
| (in English) | There is still no effective treatment for Alzheimer's disease (AD), and symptomatic treatment with drugs has extremely low treatment satisfaction due to side effects and financial burdens. To solve this problem, light stimulation therapy is attracting attention. This therapy aims to improve cognitive function by inducing the gamma frequency band of the brain waves through the presentation of light stimuli that flash at approximately 40 Hz. This therapy is characterized by fewer side effects and lower financial burden and is effective in improving satisfaction with AD treatment. Continuity of light stimulation therapy is essential, and one hour of treatment daily is recommended. However, flashing light stimulation is very cumbersome, and the limitations of the device make it impossible to work while using the device, making treatment continuity problematic. In this study, we propose a glass-type device that presents low-stress light stimuli called ISF (Invisible Spectral Flicker) stimulation in the peripheral visual field. In this study, we created a prototype capable of generating ISF stimuli and conducted the following two experiments. One is an optical characterization experiment to confirm that each LED light meets the requirements for flicker frequency, luminance, color, and spectrum. The second was a flicker intensity evaluation experiment to verify that the flickering intensity of the generated ISF stimulus was significantly lower than that of the flashing stimulus. The experimental results showed that the optical stimuli of the device met the requirements, and the flickering intensity of the ISF stimuli was significantly lower than that of the flashing stimuli. These results suggest that this device may be able to enhance the continuity of light stimulation therapy. |
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| Keyword | (in Japanese) | (See Japanese page) |
| (in English) | dementia / Alzheimer's disease / gamma entrainment / / / Head mounted device / light stimulation therapy / | |
| Reference Info. | IEICE Tech. Rep., vol. 122, no. 440, MVE2022-120, pp. 369-374, March 2023. | |
| Paper # | MVE2022-120 | |
| Date of Issue | 2023-03-08 (IMQ, IE, MVE) | |
| ISSN | Online edition: ISSN 2432-6380 | |
| Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) | |
| Download PDF | IMQ2022-90 IE2022-167 MVE2022-120 |
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| Conference Information | |
| Committee | IMQ IE MVE CQ |
| Conference Date | 2023-03-15 - 2023-03-17 |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Okinawaken Seinenkaikan (Naha-shi) |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | Media of five senses, Multimedia, Media experience, Picture codinge, Image media quality, Network,quality and reliability, etc（AC） |
| Paper Information | |
| Registration To | MVE |
| Conference Code | 2023-03-IMQ-IE-MVE-CQ |
| Language | Japanese |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Development of a low-stress light stimulation device for daily Alzheimer's disease treatment |
| Sub Title (in English) | |
| Keyword(1) | dementia |
| Keyword(2) | Alzheimer's disease |
| Keyword(3) | gamma entrainment |
| Keyword(4) | |
| Keyword(5) | |
| Keyword(6) | Head mounted device |
| Keyword(7) | light stimulation therapy |
| Keyword(8) | |
| 1st Author's Name | Yuki Yamaoka |
| 1st Author's Affiliation | Nara Institute of Science and Technology (NAIST) |
| 2nd Author's Name | Monica Perusquia-Hernandez |
| 2nd Author's Affiliation | Nara Institute of Science and Technology (NAIST) |
| 3rd Author's Name | Naoya Isoyama |
| 3rd Author's Affiliation | Nara Institute of Science and Technology (NAIST) |
| 4th Author's Name | Hideaki Uchiyama |
| 4th Author's Affiliation | Nara Institute of Science and Technology (NAIST) |
| 5th Author's Name | Kiyoshi Kiyokawa |
| 5th Author's Affiliation | Nara Institute of Science and Technology (NAIST) |
| 6th Author's Name | Takeshi Morimoto |
| 6th Author's Affiliation | Osaka University (OU) |
| Speaker | Author-1 |
| Date Time | 2023-03-17 16:05:00 |
| Presentation Time | 25 minutes |
| Registration for | MVE |
| Paper # | IMQ2022-90, IE2022-167, MVE2022-120 |
| Volume (vol) | vol.122 |
| Number (no) | no.437(IMQ), no.439(IE), no.440(MVE) |
| Page | pp.369-374 |
| #Pages | 6 |
| Date of Issue | 2023-03-08 (IMQ, IE, MVE) |
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