| Paper Abstract and Keywords |
| Presentation |
2025-01-21 13:05
* Kazuya Nishimura (NCC), Ryoma Bise (Kyushu Univ.), Yasuhiro Kojima (NCC) PRMU2024-34 |
| Abstract |
(in Japanese) |
(See Japanese page) |
| (in English) |
Spatial transcriptomics (ST) is a novel technique that simultaneously captures pathological images and gene expression profiling with spatial coordinates. Since ST is closely linked to pathological features such as disease subtypes, it may be valuable for augmenting image representation with pathological information. However, there are no attempts to leverage ST for image recognition ({it i.e,} path-level classification of subtypes of pathological image.). One of the big challenges is significant batch effects in spatial transcriptomics that make it difficult to extract pathological features of images from ST.
In this paper, we propose a batch-agnostic contrastive learning framework that can extract consistent signals from gene expression of ST in multiple patients.
To extract consistent signals from ST, we utilize the batch-agnostic gene encoder that is trained in a variational inference manner.
Experiments demonstrated the effectiveness of our framework on a publicly available dataset. |
| Keyword |
(in Japanese) |
(See Japanese page) |
| (in English) |
pathological image / contrastive learning / multi-modal learning / spatial transcriptomics / / / / |
| Reference Info. |
IEICE Tech. Rep., vol. 124, no. 336, PRMU2024-34, pp. 7-11, Jan. 2025. |
| Paper # |
PRMU2024-34 |
| Date of Issue |
2025-01-14 (PRMU) |
| ISSN |
Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
| Download PDF |
PRMU2024-34 |
| Conference Information |
| Committee |
PRMU IPSJ-CVIM VRSJ-SIG-MR MVE |
| Conference Date |
2025-01-21 - 2025-01-22 |
| Place (in Japanese) |
(See Japanese page) |
| Place (in English) |
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| Topics (in Japanese) |
(See Japanese page) |
| Topics (in English) |
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| Paper Information |
| Registration To |
PRMU |
| Conference Code |
2025-01-PRMU-CVIM-SIG-MR-MVE |
| Language |
Japanese |
| Title (in Japanese) |
(See Japanese page) |
| Sub Title (in Japanese) |
(See Japanese page) |
| Title (in English) |
* |
| Sub Title (in English) |
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| Keyword(1) |
pathological image |
| Keyword(2) |
contrastive learning |
| Keyword(3) |
multi-modal learning |
| Keyword(4) |
spatial transcriptomics |
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| 1st Author's Name |
Kazuya Nishimura |
| 1st Author's Affiliation |
National Cancer Center (NCC) |
| 2nd Author's Name |
Ryoma Bise |
| 2nd Author's Affiliation |
Kyushu University (Kyushu Univ.) |
| 3rd Author's Name |
Yasuhiro Kojima |
| 3rd Author's Affiliation |
National Cancer Center (NCC) |
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| Speaker |
Author-1 |
| Date Time |
2025-01-21 13:05:00 |
| Presentation Time |
15 minutes |
| Registration for |
PRMU |
| Paper # |
PRMU2024-34 |
| Volume (vol) |
vol.124 |
| Number (no) |
no.336 |
| Page |
pp.7-11 |
| #Pages |
5 |
| Date of Issue |
2025-01-14 (PRMU) |