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Paper Abstract and Keywords
Presentation 2026-03-06 16:06
Rat dorsal microcirculation observation and activated clotting time measurement toward real-time monitoring of blood coagulation function
Kosei Sasaki, Yuki Morimoto, Takayuki Okamoto (Chiba Univ.), Eiichi Kobayashi (Chiba Medical Center), Tomoyoshi Ito, Hideaki Haneishi (Chiba Univ.) MI2025-114
Abstract (in Japanese) (See Japanese page) 
(in English) Blood coagulation testing is essential for monitoring coagulation function during catheterization and extracorporeal circulation. Given the pharmacological properties of the anticoagulants administered during these procedures, testing every few tens of minutes imposes significant clinical burdens and inability to monitor coagulability in real time. This study aims to establish a continuous monitoring method for blood coagulation capacity by analyzing microcirculatory dynamics. In this presentation, we report on the results of microcirculatory imaging of the dorsal region and the measurement of activated clotting time (ACT) in rat models administered with heparin sodium. Our results suggested that it exists a potential correlation between ACT and blood flow velocity and blood flow velocity will be able to become a key to estimate blood coagulability.
Keyword (in Japanese) (See Japanese page) 
(in English) Microcirculation / Activated clotting time / Blood flow velocity / Heparin sodium / / / /  
Reference Info. IEICE Tech. Rep., vol. 125, no. 395, MI2025-114, pp. 199-202, March 2026.
Paper # MI2025-114 
Date of Issue 2026-02-26 (MI) 
ISSN Online edition: ISSN 2432-6380
Copyright
and
reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF MI2025-114

Conference Information
Committee MI  
Conference Date 2026-03-05 - 2026-03-06 
Place (in Japanese) (See Japanese page) 
Place (in English) OKINAWAKEN SEINENKAIKAN 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Medical Imaging, etc. 
Paper Information
Registration To MI 
Conference Code 2026-03-MI 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Rat dorsal microcirculation observation and activated clotting time measurement toward real-time monitoring of blood coagulation function 
Sub Title (in English)  
Keyword(1) Microcirculation  
Keyword(2) Activated clotting time  
Keyword(3) Blood flow velocity  
Keyword(4) Heparin sodium  
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1st Author's Name Kosei Sasaki  
1st Author's Affiliation Chiba University (Chiba Univ.)
2nd Author's Name Yuki Morimoto  
2nd Author's Affiliation Chiba University (Chiba Univ.)
3rd Author's Name Takayuki Okamoto  
3rd Author's Affiliation Chiba University (Chiba Univ.)
4th Author's Name Eiichi Kobayashi  
4th Author's Affiliation Chiba Medical Center (Chiba Medical Center)
5th Author's Name Tomoyoshi Ito  
5th Author's Affiliation Chiba University (Chiba Univ.)
6th Author's Name Hideaki Haneishi  
6th Author's Affiliation Chiba University (Chiba Univ.)
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Speaker Author-1 
Date Time 2026-03-06 16:06:00 
Presentation Time 13 minutes 
Registration for MI 
Paper # MI2025-114 
Volume (vol) vol.125 
Number (no) no.395 
Page pp.199-202 
#Pages 4 
Date of Issue 2026-02-26 (MI) 

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