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Paper Abstract and Keywords
Presentation 2008-07-10 10:55
Electrical Detection of Si-Tagged Proteins on HF-last Si(100) and Thermally Grown SiO2 Surfaces
S. Mahboob, Katsunori Makihara, Hirotaka Kaku, Mitsuhisa Ikeda, Seiichiro Higashi, Seiichi Miyazaki, Akio Kuroda (Hiroshima Univ.) ED2008-69 SDM2008-88
Abstract (in Japanese) (See Japanese page) 
(in English) We successfully detected silicon-binding proteins such as Si-tagged protein A, green fluorescent protein (GFP) and luciferase attached to OH-terminated SiO2 and H-terminated Si surfaces by surface potential measurements using an AFM/Kelvin probe technique. We also observed significant change in electrical conductivity of lightly phosphorous doped poly-Si films after attachment of Si-tagged proteins. The conductivity of the poly-Si films is increased from 1.0x10-5 S/cm to 3.7x10-4 S/cm with the attachment of protein A. It is suggested that field effect passivation of unoccupied gap states in polycrystalline Si film increased the film conductivity. These results will open up the fabrication of a sensing device for locally ionized biomolecules.
Keyword (in Japanese) (See Japanese page) 
(in English) Biosensor / Si-tagged Protein A / green fluorescent protein / luciferase / KFM / / /  
Reference Info. IEICE Tech. Rep., vol. 108, no. 122, SDM2008-88, pp. 155-158, July 2008.
Paper # SDM2008-88 
Date of Issue 2008-07-02 (ED, SDM) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
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All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee SDM ED  
Conference Date 2008-07-09 - 2008-07-11 
Place (in Japanese) (See Japanese page) 
Place (in English) Kaderu2・7 
Topics (in Japanese) (See Japanese page) 
Topics (in English) 2008 Asia-Pacific Workshop on Fundamentals and Applications of Advanced Semiconductor Devices 
Paper Information
Registration To SDM 
Conference Code 2008-07-SDM-ED 
Language English 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Electrical Detection of Si-Tagged Proteins on HF-last Si(100) and Thermally Grown SiO2 Surfaces 
Sub Title (in English)  
Keyword(1) Biosensor  
Keyword(2) Si-tagged Protein A  
Keyword(3) green fluorescent protein  
Keyword(4) luciferase  
Keyword(5) KFM  
Keyword(6)  
Keyword(7)  
Keyword(8)  
1st Author's Name S. Mahboob  
1st Author's Affiliation Hiroshima University (Hiroshima Univ.)
2nd Author's Name Katsunori Makihara  
2nd Author's Affiliation Hiroshima University (Hiroshima Univ.)
3rd Author's Name Hirotaka Kaku  
3rd Author's Affiliation Hiroshima University (Hiroshima Univ.)
4th Author's Name Mitsuhisa Ikeda  
4th Author's Affiliation Hiroshima University (Hiroshima Univ.)
5th Author's Name Seiichiro Higashi  
5th Author's Affiliation Hiroshima University (Hiroshima Univ.)
6th Author's Name Seiichi Miyazaki  
6th Author's Affiliation Hiroshima University (Hiroshima Univ.)
7th Author's Name Akio Kuroda  
7th Author's Affiliation Hiroshima University (Hiroshima Univ.)
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Speaker Author-1 
Date Time 2008-07-10 10:55:00 
Presentation Time 15 minutes 
Registration for SDM 
Paper # ED2008-69, SDM2008-88 
Volume (vol) vol.108 
Number (no) no.121(ED), no.122(SDM) 
Page pp.155-158 
#Pages
Date of Issue 2008-07-02 (ED, SDM) 


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