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Paper Abstract and Keywords
Presentation 2009-06-25 12:15
Electrical Detection of Silicon Binding Protein-Protein A Using a p-MOSFET Sensor
Hideki Murakami, Syed Mahboob, Kiyotaka Katayama, Katsunori Makihara, Mitsuhisa Ikeda, Yumehiro Hata, Akio Kuroda, Seiichiro Higashi, Seiichi Miyazaki (Hiroshima Univ.) ED2009-87 SDM2009-82
Abstract (in Japanese) (See Japanese page) 
(in English) We have focused on silica binding protein(SBP)-tagged protein A as a key element for bio-sensing since this combined protein can act as an anchor for variety of target bio-molecules￢ on Si and SiO2 surfaces In this work, we confirmed the change in the surface potential with an attachment of SBP-tagged protein A on Si and SiO2, and clearly observed an increase in conductivity of undoped poly-Si thin film on thermally -grown SiO2 just after the attachment of silica binding protein-protein A on the surface. These results can be attributable to the change in the surface band bending of the poly-Si film. In p-channel FETs with a SiO2/Si3N4 gate dielectric, the drain current was significantly decreased by the attachment of the SBP-tagged protein A. Observed decrease in the drain current can be interpreted in terms of screening of pre-existing negative charges at the interface between SiO2and Si3N4 and in the Si3N4 film with the attachment of electrically-polarized SBP-protein A.
Keyword (in Japanese) (See Japanese page) 
(in English) Biosensor / Silica binding protein / / / / / /  
Reference Info. IEICE Tech. Rep., vol. 109, no. 98, SDM2009-82, pp. 161-164, June 2009.
Paper # SDM2009-82 
Date of Issue 2009-06-17 (ED, SDM) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
and
reproduction		 All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee SDM ED  
Conference Date 2009-06-24 - 2009-06-26 
Place (in Japanese) (See Japanese page) 
Place (in English) Haeundae Grand Hotel, Busan, Korea 
Topics (in Japanese) (See Japanese page) 
Topics (in English) 2009 Asia-Pacific Workshop on Fundamentals and Applications of Advanced Semiconductor Devices 
Paper Information
Registration To SDM 
Conference Code 2009-06-SDM-ED 
Language English 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Electrical Detection of Silicon Binding Protein-Protein A Using a p-MOSFET Sensor 
Sub Title (in English)  
Keyword(1) Biosensor  
Keyword(2) Silica binding protein  
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1st Author's Name Hideki Murakami  
1st Author's Affiliation Hiroshima university (Hiroshima Univ.)
2nd Author's Name Syed Mahboob  
2nd Author's Affiliation Hiroshima university (Hiroshima Univ.)
3rd Author's Name Kiyotaka Katayama  
3rd Author's Affiliation Hiroshima university (Hiroshima Univ.)
4th Author's Name Katsunori Makihara  
4th Author's Affiliation Hiroshima university (Hiroshima Univ.)
5th Author's Name Mitsuhisa Ikeda  
5th Author's Affiliation Hiroshima university (Hiroshima Univ.)
6th Author's Name Yumehiro Hata  
6th Author's Affiliation Hiroshima university (Hiroshima Univ.)
7th Author's Name Akio Kuroda  
7th Author's Affiliation Hiroshima university (Hiroshima Univ.)
8th Author's Name Seiichiro Higashi  
8th Author's Affiliation Hiroshima university (Hiroshima Univ.)
9th Author's Name Seiichi Miyazaki  
9th Author's Affiliation Hiroshima university (Hiroshima Univ.)
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Speaker Author-1 
Date Time 2009-06-25 12:15:00 
Presentation Time 15 minutes 
Registration for SDM 
Paper # ED2009-87, SDM2009-82 
Volume (vol) vol.109 
Number (no) no.97(ED), no.98(SDM) 
Page pp.161-164 
#Pages 4 
Date of Issue 2009-06-17 (ED, SDM) 

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