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| Presentation | 2010-03-10 10:40 A Study on Path Following of Label-Permuted Solution for Support Vector Machine and its Application for Microarray Data Analysis Yuta Ishikawa, Kouta Isobe, Ichiro Takeuchi (Nagoya Inst. of Tech.)  NC2009-132 |
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| Abstract | (in Japanese) | (See Japanese page) |
| (in English) | Microarray technology enables us to measure expression levels of thousands of genes simultaneously.The fundamental task of microarray data analysis is to find differentially expressed genes between two samples. In this study we consider how to find differentially expressed gene sets rather than individual genes) between two samples. This task is called gene set analysis and it is mathematically formulated as multivariate two-sample test. As an approach of gene set analysis, we introduce a multivariate two-sample test whose test statistic is given by the classification error of support vector machine (SVM) classifier. The null distribution of the statistic is computed based on label permutation operation, and thus we need to train many SVM classifiers for permuted labels. In this paper we are concerned with the problem of reducing the computational cost of this operation by proposing a path-following algorithm to compute the path of label-permuted SVM classifiers. |
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| Keyword | (in Japanese) | (See Japanese page) |
| (in English) | Support Vector Machine / Path Following / Label-Permutation / Microarray / GSEA / / / | |
| Reference Info. | IEICE Tech. Rep., vol. 109, no. 461, NC2009-132, pp. 261-266, March 2010. | |
| Paper # | NC2009-132 | |
| Date of Issue | 2010-03-02 (NC) | |
| ISSN | Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 | |
| Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) | |
| Download PDF | NC2009-132 |
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| Conference Information | |
| Committee | NC MBE |
| Conference Date | 2010-03-09 - 2010-03-11 |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Tamagawa University |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | General |
| Paper Information | |
| Registration To | NC |
| Conference Code | 2010-03-NC-MBE |
| Language | Japanese |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | A Study on Path Following of Label-Permuted Solution for Support Vector Machine and its Application for Microarray Data Analysis |
| Sub Title (in English) | |
| Keyword(1) | Support Vector Machine |
| Keyword(2) | Path Following |
| Keyword(3) | Label-Permutation |
| Keyword(4) | Microarray |
| Keyword(5) | GSEA |
| Keyword(6) | |
| Keyword(7) | |
| Keyword(8) | |
| 1st Author's Name | Yuta Ishikawa |
| 1st Author's Affiliation | Nagoya Institute of Technology (Nagoya Inst. of Tech.) |
| 2nd Author's Name | Kouta Isobe |
| 2nd Author's Affiliation | Nagoya Institute of Technology (Nagoya Inst. of Tech.) |
| 3rd Author's Name | Ichiro Takeuchi |
| 3rd Author's Affiliation | Nagoya Institute of Technology (Nagoya Inst. of Tech.) |
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| Speaker | Author-1 |
| Date Time | 2010-03-10 10:40:00 |
| Presentation Time | 25 minutes |
| Registration for | NC |
| Paper # | NC2009-132 |
| Volume (vol) | vol.109 |
| Number (no) | no.461 |
| Page | pp.261-266 |
| #Pages | 6 |
| Date of Issue | 2010-03-02 (NC) |
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