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Paper Abstract and Keywords
Presentation 2010-11-15 14:40
Preparation of glass beads incorporating quantum dots for use as fluorescent reagent and neuronal cell imaging
Masanori Ando, Chunliang Li, Ping Yang, Norio Murase, Chie Hosokawa, Takahisa Taguchi (AIST) MI2010-76
Abstract (in Japanese) (See Japanese page) 
(in English) Quantum dots (QDs) show bright photoluminescence whose emission wavelength can be controlled by their particle size and composition. Compared with organic fluorescent dyes, QDs are more resistant to light irradiation. Because of those advantages, QDs attract much interest as novel bright fluorescent reagents. Photoluminescent QDs are synthesized in solution. However, QDs in solution are not very stable and tend to degradate. Therefore, we developed techniques to incorporate multiple QDs such as CdSe and InP in a small glass bead (diameter: several tens nm) by using sol-gel method at room temperature and under atmospheric pressure. The QD-incorporating glass beads are water-dispersible and emit bright photoluminescence. When dispersed in buffer solution for biological use, the glass beads showed much higher stability and light-resistance than commercial polymer-coated QDs. It was possible to obtain high-resolution fluorescence image of living neuronal cells by introducing the glass beads in the cells by endocytosis.
Keyword (in Japanese) (See Japanese page) 
(in English) Quantum dot (QD) / Glass / Bead / Photoluminescence / Fluorescent reagent / Neuronal cell / Imaging /  
Reference Info. IEICE Tech. Rep., vol. 110, no. 280, MI2010-76, pp. 57-62, Nov. 2010.
Paper # MI2010-76 
Date of Issue 2010-11-08 (MI) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
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All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee MI  
Conference Date 2010-11-15 - 2010-11-15 
Place (in Japanese) (See Japanese page) 
Place (in English) Shimadzu Corp. 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Medical Imaging 
Paper Information
Registration To MI 
Conference Code 2010-11-MI 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Preparation of glass beads incorporating quantum dots for use as fluorescent reagent and neuronal cell imaging 
Sub Title (in English)  
Keyword(1) Quantum dot (QD)  
Keyword(2) Glass  
Keyword(3) Bead  
Keyword(4) Photoluminescence  
Keyword(5) Fluorescent reagent  
Keyword(6) Neuronal cell  
Keyword(7) Imaging  
Keyword(8)  
1st Author's Name Masanori Ando  
1st Author's Affiliation National Institute of Advanced Industrial Science and Technology (AIST)
2nd Author's Name Chunliang Li  
2nd Author's Affiliation National Institute of Advanced Industrial Science and Technology (AIST)
3rd Author's Name Ping Yang  
3rd Author's Affiliation National Institute of Advanced Industrial Science and Technology (AIST)
4th Author's Name Norio Murase  
4th Author's Affiliation National Institute of Advanced Industrial Science and Technology (AIST)
5th Author's Name Chie Hosokawa  
5th Author's Affiliation National Institute of Advanced Industrial Science and Technology (AIST)
6th Author's Name Takahisa Taguchi  
6th Author's Affiliation National Institute of Advanced Industrial Science and Technology (AIST)
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Speaker Author-1 
Date Time 2010-11-15 14:40:00 
Presentation Time 25 minutes 
Registration for MI 
Paper # MI2010-76 
Volume (vol) vol.110 
Number (no) no.280 
Page pp.57-62 
#Pages
Date of Issue 2010-11-08 (MI) 


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