| Paper Abstract and Keywords |
| Presentation |
2020-12-14 16:20
The physiological protocol of temporary BBB opening by High Intensity Ultrasound
-- To deliver the anti-cancer drug to the affected area of glioblastoma smoothly -- Kazuhide Okada (NTMC) US2020-55 |
| Abstract |
(in Japanese) |
(See Japanese page) |
| (in English) |
In case of one of serious brain tumour, glioblastoma whose cure rate is pretty low,
the promising therapy is to pass the anti-tumour drug from blood side to the brain side,
by irradiating ultrasound to BBB attached with the blood vessel in which microbubbles are filled by the intravenous injection prior to its therapy, to open TJ (tight junction) of BBB.
But BBB is the important path which transmit the lactate and the amino acid to the whole body. So it must be closed as soon as the said drug cross BBB. So, In this study how to open/ close BBB physically and concretely is discussed. |
| Keyword |
(in Japanese) |
(See Japanese page) |
| (in English) |
glicoma / glioblastoma / HIFU / BBB / Tight Junction / microbubble / intravenous injection / |
| Reference Info. |
IEICE Tech. Rep., vol. 120, no. 295, US2020-55, pp. 28-33, Dec. 2020. |
| Paper # |
US2020-55 |
| Date of Issue |
2020-12-07 (US) |
| ISSN |
Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
| Download PDF |
US2020-55 |
| Conference Information |
| Committee |
US |
| Conference Date |
2020-12-14 - 2020-12-14 |
| Place (in Japanese) |
(See Japanese page) |
| Place (in English) |
Online |
| Topics (in Japanese) |
(See Japanese page) |
| Topics (in English) |
|
| Paper Information |
| Registration To |
US |
| Conference Code |
2020-12-US |
| Language |
English (Japanese title is available) |
| Title (in Japanese) |
(See Japanese page) |
| Sub Title (in Japanese) |
(See Japanese page) |
| Title (in English) |
The physiological protocol of temporary BBB opening by High Intensity Ultrasound |
| Sub Title (in English) |
To deliver the anti-cancer drug to the affected area of glioblastoma smoothly |
| Keyword(1) |
glicoma |
| Keyword(2) |
glioblastoma |
| Keyword(3) |
HIFU |
| Keyword(4) |
BBB |
| Keyword(5) |
Tight Junction |
| Keyword(6) |
microbubble |
| Keyword(7) |
intravenous injection |
| Keyword(8) |
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| 1st Author's Name |
Kazuhide Okada |
| 1st Author's Affiliation |
New Tokyo Medical College (NTMC) |
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| Speaker |
Author-1 |
| Date Time |
2020-12-14 16:20:00 |
| Presentation Time |
25 minutes |
| Registration for |
US |
| Paper # |
US2020-55 |
| Volume (vol) |
vol.120 |
| Number (no) |
no.295 |
| Page |
pp.28-33 |
| #Pages |
6 |
| Date of Issue |
2020-12-07 (US) |