IEICE Technical Committee Submission System
Conference Paper's Information
Online Proceedings
[Sign in]
Tech. Rep. Archives
 Go Top Page Go Previous   [Japanese] / [English] 

Paper Abstract and Keywords
Presentation 2020-12-14 16:20
The physiological protocol of temporary BBB opening by High Intensity Ultrasound -- To deliver the anti-cancer drug to the affected area of glioblastoma smoothly --
Kazuhide Okada (NTMC) US2020-55
Abstract (in Japanese) (See Japanese page) 
(in English) In case of one of serious brain tumour, glioblastoma whose cure rate is pretty low,
the promising therapy is to pass the anti-tumour drug from blood side to the brain side,
by irradiating ultrasound to BBB attached with the blood vessel in which microbubbles are filled by the intravenous injection prior to its therapy, to open TJ (tight junction) of BBB.
But BBB is the important path which transmit the lactate and the amino acid to the whole body. So it must be closed as soon as the said drug cross BBB. So, In this study how to open/ close BBB physically and concretely is discussed.
Keyword (in Japanese) (See Japanese page) 
(in English) glicoma / glioblastoma / HIFU / BBB / Tight Junction / microbubble / intravenous injection /  
Reference Info. IEICE Tech. Rep., vol. 120, no. 295, US2020-55, pp. 28-33, Dec. 2020.
Paper # US2020-55 
Date of Issue 2020-12-07 (US) 
ISSN Online edition: ISSN 2432-6380
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF US2020-55

Conference Information
Committee US  
Conference Date 2020-12-14 - 2020-12-14 
Place (in Japanese) (See Japanese page) 
Place (in English) Online 
Topics (in Japanese) (See Japanese page) 
Topics (in English)  
Paper Information
Registration To US 
Conference Code 2020-12-US 
Language English (Japanese title is available) 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) The physiological protocol of temporary BBB opening by High Intensity Ultrasound 
Sub Title (in English) To deliver the anti-cancer drug to the affected area of glioblastoma smoothly 
Keyword(1) glicoma  
Keyword(2) glioblastoma  
Keyword(3) HIFU  
Keyword(4) BBB  
Keyword(5) Tight Junction  
Keyword(6) microbubble  
Keyword(7) intravenous injection  
1st Author's Name Kazuhide Okada  
1st Author's Affiliation New Tokyo Medical College (NTMC)
2nd Author's Name  
2nd Author's Affiliation ()
3rd Author's Name  
3rd Author's Affiliation ()
4th Author's Name  
4th Author's Affiliation ()
5th Author's Name  
5th Author's Affiliation ()
6th Author's Name  
6th Author's Affiliation ()
7th Author's Name  
7th Author's Affiliation ()
8th Author's Name  
8th Author's Affiliation ()
9th Author's Name  
9th Author's Affiliation ()
10th Author's Name  
10th Author's Affiliation ()
11th Author's Name  
11th Author's Affiliation ()
12th Author's Name  
12th Author's Affiliation ()
13th Author's Name  
13th Author's Affiliation ()
14th Author's Name  
14th Author's Affiliation ()
15th Author's Name  
15th Author's Affiliation ()
16th Author's Name  
16th Author's Affiliation ()
17th Author's Name  
17th Author's Affiliation ()
18th Author's Name  
18th Author's Affiliation ()
19th Author's Name  
19th Author's Affiliation ()
20th Author's Name  
20th Author's Affiliation ()
Speaker Author-1 
Date Time 2020-12-14 16:20:00 
Presentation Time 25 minutes 
Registration for US 
Paper # US2020-55 
Volume (vol) vol.120 
Number (no) no.295 
Page pp.28-33 
Date of Issue 2020-12-07 (US) 

[Return to Top Page]

[Return to IEICE Web Page]

The Institute of Electronics, Information and Communication Engineers (IEICE), Japan