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Paper Abstract and Keywords
Presentation 2024-03-11 16:00
An analysis of evoked-response dynamics with a simple synaptic plasticity model upon long-term depression in the auditory cortex -- Exploration of major neurotransmitter receptors for an induction of depression --
Ryo Furukawa, Takashi Tateno (Hokkaido Univ.) NC2023-47
Abstract (in Japanese) (See Japanese page) 
(in English) In the context of neurotransmitter receptors within the central nervous system, the efficient selection in advance of key candidates related to auditory cortical synaptic plasticity could enable us to perform physiological experiments more efficiently. Several simple models have already been proposed to describe the response dynamics after the induction of neural plasticity. Here, we initially measured cortical responses to electrical stimulation after inducing plasticity under several pharmacological conditions, manipulating both control and receptor-modulated groups. Subsequently, between the groups, we estimated and compared the coefficients of the dynamic model describing the electric-pulse-driven responses after the synaptic plasticity induction. Then, we discuss the main receptors involved in the neural plasticity of the auditory cortex, as elucidated by a simple model. Finally, drawing from the outcomes of this study, we discuss prospective challenges for future applied research.
Keyword (in Japanese) (See Japanese page) 
(in English) Auditory cortex / Brain slice / Long-term depression / Synaptic plasticity model / / / /  
Reference Info. IEICE Tech. Rep., vol. 123, no. 418, NC2023-47, pp. 25-30, March 2024.
Paper # NC2023-47 
Date of Issue 2024-03-04 (NC) 
ISSN Online edition: ISSN 2432-6380
Copyright
and
reproduction
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF NC2023-47

Conference Information
Committee NC MBE  
Conference Date 2024-03-11 - 2024-03-12 
Place (in Japanese) (See Japanese page) 
Place (in English) The Univ. of Tokyo 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Brain architecture, General 
Paper Information
Registration To NC 
Conference Code 2024-03-NC-MBE 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) An analysis of evoked-response dynamics with a simple synaptic plasticity model upon long-term depression in the auditory cortex 
Sub Title (in English) Exploration of major neurotransmitter receptors for an induction of depression 
Keyword(1) Auditory cortex  
Keyword(2) Brain slice  
Keyword(3) Long-term depression  
Keyword(4) Synaptic plasticity model  
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1st Author's Name Ryo Furukawa  
1st Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University (Hokkaido Univ.)
2nd Author's Name Takashi Tateno  
2nd Author's Affiliation Faculty of Information Science and Technology, Hokkaido University (Hokkaido Univ.)
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Speaker Author-1 
Date Time 2024-03-11 16:00:00 
Presentation Time 25 minutes 
Registration for NC 
Paper # NC2023-47 
Volume (vol) vol.123 
Number (no) no.418 
Page pp.25-30 
#Pages
Date of Issue 2024-03-04 (NC) 


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