Paper Abstract and Keywords |
Presentation |
2024-03-11 16:00
An analysis of evoked-response dynamics with a simple synaptic plasticity model upon long-term depression in the auditory cortex
-- Exploration of major neurotransmitter receptors for an induction of depression -- Ryo Furukawa, Takashi Tateno (Hokkaido Univ.) NC2023-47 |
Abstract |
(in Japanese) |
(See Japanese page) |
(in English) |
In the context of neurotransmitter receptors within the central nervous system, the efficient selection in advance of key candidates related to auditory cortical synaptic plasticity could enable us to perform physiological experiments more efficiently. Several simple models have already been proposed to describe the response dynamics after the induction of neural plasticity. Here, we initially measured cortical responses to electrical stimulation after inducing plasticity under several pharmacological conditions, manipulating both control and receptor-modulated groups. Subsequently, between the groups, we estimated and compared the coefficients of the dynamic model describing the electric-pulse-driven responses after the synaptic plasticity induction. Then, we discuss the main receptors involved in the neural plasticity of the auditory cortex, as elucidated by a simple model. Finally, drawing from the outcomes of this study, we discuss prospective challenges for future applied research. |
Keyword |
(in Japanese) |
(See Japanese page) |
(in English) |
Auditory cortex / Brain slice / Long-term depression / Synaptic plasticity model / / / / |
Reference Info. |
IEICE Tech. Rep., vol. 123, no. 418, NC2023-47, pp. 25-30, March 2024. |
Paper # |
NC2023-47 |
Date of Issue |
2024-03-04 (NC) |
ISSN |
Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
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NC2023-47 |
Conference Information |
Committee |
NC MBE |
Conference Date |
2024-03-11 - 2024-03-12 |
Place (in Japanese) |
(See Japanese page) |
Place (in English) |
The Univ. of Tokyo |
Topics (in Japanese) |
(See Japanese page) |
Topics (in English) |
Brain architecture, General |
Paper Information |
Registration To |
NC |
Conference Code |
2024-03-NC-MBE |
Language |
Japanese |
Title (in Japanese) |
(See Japanese page) |
Sub Title (in Japanese) |
(See Japanese page) |
Title (in English) |
An analysis of evoked-response dynamics with a simple synaptic plasticity model upon long-term depression in the auditory cortex |
Sub Title (in English) |
Exploration of major neurotransmitter receptors for an induction of depression |
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Auditory cortex |
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Brain slice |
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Long-term depression |
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Synaptic plasticity model |
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1st Author's Name |
Ryo Furukawa |
1st Author's Affiliation |
Graduate School of Information Science and Technology, Hokkaido University (Hokkaido Univ.) |
2nd Author's Name |
Takashi Tateno |
2nd Author's Affiliation |
Faculty of Information Science and Technology, Hokkaido University (Hokkaido Univ.) |
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Speaker |
Author-1 |
Date Time |
2024-03-11 16:00:00 |
Presentation Time |
25 minutes |
Registration for |
NC |
Paper # |
NC2023-47 |
Volume (vol) |
vol.123 |
Number (no) |
no.418 |
Page |
pp.25-30 |
#Pages |
6 |
Date of Issue |
2024-03-04 (NC) |
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