| Paper Abstract and Keywords |
| Presentation |
2022-03-01 17:05
Construction of a fluorescence imaging system for electric field measurement in lipid bilayers Maki Komiya, Daiki Ando, Hironori Kageyama, Takaya Watanabe, Madoka Sato, Teng Ma (Tohoku Univ), Kensaku Kanomata, Fumihiko Hirose (Yamagata Univ), Ayumi Hirano-Iwata (Tohoku Univ) CPM2021-85 |
| Abstract |
(in Japanese) |
(See Japanese page) |
| (in English) |
Ion channels, one of the transmembrane proteins, play important roles in biological activities. We have been developing analytical systems using artificial lipid bilayers to evaluate the mechanism of those ion channel proteins. In our recent study, we found that the electric field generated by the application of a voltage parallel to the lipid bilayer membrane affects the transmembrane current of the voltage-gated sodium ion channel (Nav1.5) embedded in the membrane. However, the mechanism of this phenomenon has not yet been revealed. Therefore, in this study, in order to clarify the mechanism, we had constructed a fluorescence imaging system for detecting the electric field in lipid bilayer membranes using voltage-sensitive dyes. |
| Keyword |
(in Japanese) |
(See Japanese page) |
| (in English) |
artificial cell membrane / ion channels / / / / / / |
| Reference Info. |
IEICE Tech. Rep., vol. 121, no. 387, CPM2021-85, pp. 48-49, March 2022. |
| Paper # |
CPM2021-85 |
| Date of Issue |
2022-02-22 (CPM) |
| ISSN |
Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
| Download PDF |
CPM2021-85 |
| Conference Information |
| Committee |
CPM |
| Conference Date |
2022-03-01 - 2022-03-01 |
| Place (in Japanese) |
(See Japanese page) |
| Place (in English) |
Online |
| Topics (in Japanese) |
(See Japanese page) |
| Topics (in English) |
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| Paper Information |
| Registration To |
CPM |
| Conference Code |
2022-03-CPM |
| Language |
Japanese |
| Title (in Japanese) |
(See Japanese page) |
| Sub Title (in Japanese) |
(See Japanese page) |
| Title (in English) |
Construction of a fluorescence imaging system for electric field measurement in lipid bilayers |
| Sub Title (in English) |
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| Keyword(1) |
artificial cell membrane |
| Keyword(2) |
ion channels |
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| 1st Author's Name |
Maki Komiya |
| 1st Author's Affiliation |
Tohoku University (Tohoku Univ) |
| 2nd Author's Name |
Daiki Ando |
| 2nd Author's Affiliation |
Tohoku University (Tohoku Univ) |
| 3rd Author's Name |
Hironori Kageyama |
| 3rd Author's Affiliation |
Tohoku University (Tohoku Univ) |
| 4th Author's Name |
Takaya Watanabe |
| 4th Author's Affiliation |
Tohoku University (Tohoku Univ) |
| 5th Author's Name |
Madoka Sato |
| 5th Author's Affiliation |
Tohoku University (Tohoku Univ) |
| 6th Author's Name |
Teng Ma |
| 6th Author's Affiliation |
Tohoku University (Tohoku Univ) |
| 7th Author's Name |
Kensaku Kanomata |
| 7th Author's Affiliation |
Yamagata University (Yamagata Univ) |
| 8th Author's Name |
Fumihiko Hirose |
| 8th Author's Affiliation |
Yamagata University (Yamagata Univ) |
| 9th Author's Name |
Ayumi Hirano-Iwata |
| 9th Author's Affiliation |
Tohoku University (Tohoku Univ) |
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| Speaker |
Author-1 |
| Date Time |
2022-03-01 17:05:00 |
| Presentation Time |
15 minutes |
| Registration for |
CPM |
| Paper # |
CPM2021-85 |
| Volume (vol) |
vol.121 |
| Number (no) |
no.387 |
| Page |
pp.48-49 |
| #Pages |
2 |
| Date of Issue |
2022-02-22 (CPM) |